Protein Alignment tobi and Si

DIOPT Version :10

• Sequence 1: NP_651391.1
• Gene: tobi / 43072
• FlyBaseID: FBgn0261575
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_001376155.1
• Gene: Si / 497756
• RGDID: 3675
• Length: 1836
• Species: Rattus norvegicus
• Alignment Length: 830
• Identity: 163/830 - (19%)
• Similarity: 262/830 - (31%)
• Gaps: 286/830 - (34%)

  Fly    14 CLWEAV-----------------HTCASIE----------------QRYKFPNS-----NVYVRL 40
            |||:.|                 :|..||:                .|.|.|::     .|.|:.
  Rat   970 CLWQPVSGLSNVPPCYFPPEHNPYTLTSIQPLPTGITAELQLNPANARIKLPSNPISTLRVEVKY 1034

  Fly    41 RRGDKLQYELMKGEKSL----------QTVTFDN---FD---------------SSANLV-ETSS 76
            .:.|.||:::...:...          .|.|..|   :|               ||..|: ::|.
  Rat  1035 HKNDMLQFKIYDAQHKRYEVPVPLNIPDTPTSSNERLYDVEIKENPFGIQVRRRSSGKLIWDSSL 1099

  Fly    77 GSYQLTDGQSTVEFTLVKSGVVAGTGSEITHVKVSRDQVLQGTQPRDCVPLKTGSTHWFSGPEQK 141
            ..:...| |.....|.:.|..:.|.| |:.|....||                  .:|
  Rat  1100 PGFAFND-QFIQISTRLPSNYLYGFG-EVEHTAFKRD------------------LNW------- 1137

  Fly   142 QHYWPV-ERQRHSNYSYLPKELDNFGVGERYWL-----NGDGVFLYVESNTPLFIDQNSAAYPDQ 200
             |.|.: .|.:...|     :|:::|....|..     |..||.| :.||.   :|......|
  Rat  1138 -HTWGMFTRDQPPGY-----KLNSYGFHPYYMALENEGNAHGVLL-LNSNG---MDVTFQPTP-- 1190

  Fly   201 LCLSAISALPYDPRVTSAKFVYHVAVAKDAKAAHRYAVKTFLGQPTGYPDERMVMHPVWSTWALY 265
                   ||.|  |.......:::.:....:.|.|.     ..:..|:|    ||.|.|:
  Rat  1191 -------ALTY--RTIGGILDFYMFLGPTPEIATRQ-----YHEVIGFP----VMPPYWA----- 1232

  Fly   266 KAEVSDDVVRDFAKQILDNGFNNSQLEIDDDWEDCYGAMTFRKNKFPD---------------SK 315
                       ...|:...|:.|:. ||:..:.|...|......::.|               .|
  Rat  1233 -----------LGFQLCRYGYRNTS-EIEQLYNDMVAANIPYDVQYTDINYMERQLDFTIGERFK 1285

  Fly   316 TL---TDDLKALGFRVTLWIHPFINNNCTAIYDEAKSKGY---LVLDHEGSSDTQW---W----- 366
            ||   .|.::..|.:..:.:.|.|:.|.|..| .|..:|.   :.:....::|..|   |
  Rat  1286 TLPEFVDRIRKDGMKYIVILDPAISGNETQPY-PAFERGIQKDVFVKWPNTNDICWAKVWPDLPN 1349

  Fly   367 -------------NSKPKDAAILDFTKTEVQEWFSKRLKRLQDEDGIDSFKFDA----------- 407
                         |:.....|..||.:....||:::.:....:|    ..|||.
  Rat  1350 VTIDETITEDEAVNASRAHVAFPDFFRNSTLEWWAREIYDFYNE----KMKFDGLWIDMNEPSSF 1410

  Fly   408 --------------------------GE-----TSWLPSDPVLQASSSMV----------TPLQA 431
                                      ||     |..:.::.:|...||::          :.::.
  Rat  1411 VNGTVTNKCRNDTLNYPPYFPELTKRGEGLHFRTMCMETEHILSDGSSVLHYDVHNLYGWSQVKP 1475

  Fly   432 VGDYVRTVAAFGDMVEVRSAQNTQDQPIFVRIVDKDSEWG----------WNNGLLTLISSMLQM 486
            ..|.::.......:|..||...|.            ..||          |:|...:|| .||:.
  Rat  1476 TLDALQNTTGLRGIVISRSTYPTA------------GRWGGHWLGDNYANWDNLEKSLI-GMLEF 1527

  Fly   487 NLNGYPFVLPDMIGGNGYYEKPPTKELFLRWLQANVFMP-----ALQFSF----VPWNFDDEAIA 542
            ||.|.|::..|:.|    :.......|..||:|...|.|     .:||:.    |.||   |..|
  Rat  1528 NLFGIPYIGADICG----FFNDSEYHLCTRWMQVGAFYPYSRNHNIQFTRRQDPVSWN---ETFA 1585

  Fly   543 -ISKNFTALHATYTPYIMKLFKRAVDSGEPVNVPLWWIAPTDEVAQSIYDEFLLGEDIIAAPVVV 606
             :||....:..|..||.......|...|..|..||......|:....||.:||.|...:..|||.
  Rat  1586 QMSKKVLEIRYTLLPYFYTQMHEAHAQGGTVIRPLMHEFFDDKETWEIYKQFLWGPAFMVTPVVE 1650

  Fly   607 EGATKRDIYLPEGEWQDGNSDQVYTGPTWVMDYAAPLDTLPYFLRVGFTL 656
            ...|....|:|:..|.|.::.:.......:..::||.||:...:|.|:.|
  Rat  1651 PFRTSVTGYVPKARWFDYHTGEDIKLKGILHTFSAPFDTINLHVRGGYIL 1700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tobi	NP_651391.1	GH31_NET37	255..621	CDD:269878	96/479 (20%)
Si	NP_001376155.1	Trefoil	80..118	CDD:459666
		NtCtMGAM_N	135..245	CDD:465286
		GH31_N	237..353	CDD:270212
		GH31_MGAM_SI_GAA	353..717	CDD:269888
		PD	944..990	CDD:197472	4/19 (21%)
		NtCtMGAM_N	1004..1117	CDD:465286	19/113 (17%)
		GH31_N	1109..1223	CDD:270212	30/165 (18%)
		Glyco_hydro_31	1204..1700	CDD:460044	109/546 (20%)