Protein Alignment tobi and Gaa

DIOPT Version :10

• Sequence 1: NP_651391.1
• Gene: tobi / 43072
• FlyBaseID: FBgn0261575
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_954549.1
• Gene: Gaa / 367562
• RGDID: 735227
• Length: 953
• Species: Rattus norvegicus
• Alignment Length: 646
• Identity: 145/646 - (22%)
• Similarity: 230/646 - (35%)
• Gaps: 150/646 - (23%)

  Fly    91 TLVKSGVVAGTGSEITHVKVSRDQVLQGTQPRDCVPLKTGSTHWFSGPEQKQHYWPVERQRHSNY 155
            |.:.|..:||.|..::.:.:|.:........||..| ..|...:.|.|
  Rat   250 TSLPSQHIAGLGEHLSPLMLSTEWTRITLWNRDVAP-SQGVNLYGSHP----------------- 296

  Fly   156 SYLPKELDNFGVGERYWLNGDGVFLYVESNTPLFIDQNSAAYPDQLCLSAISALPYDPRVTSAKF 220
            .||  .|::.|:..       ||||.           ||.|.  .:.|....||.:  |.|....
  Rat   297 FYL--ALEDGGLAH-------GVFLL-----------NSNAM--DVVLQPSPALTW--RSTGGIL 337

  Fly   221 VYHVAVAKDAKAAHRYAVKTFLGQPTGYPDERMVMHPVWS------TWALYKAEVSDDVVRDFAK 279
            ..:|.:..:.|:    .|:.:| ...|||    .|.|.|.      .|......:...||.:..:
  Rat   338 DVYVFLGPEPKS----VVQQYL-DVVGYP----FMPPYWGLGFHLCRWGYSSTAIVRQVVENMTR 393

  Fly   280 Q--ILDNGFNNSQLEIDDDWEDCYGAMTFRKNKFPDSKTLTDDLKALGFRVTLWIHPFINNNCTA 342
            .  .||..:|      |.|:.|.....||.::.|.|...:..:|...|.|..:.:.|.|:::..|
  Rat   394 THFPLDVQWN------DLDYMDARRDFTFNQDGFADFPDMVHELHQGGRRYMMIVDPAISSSGPA 452

  Fly   343 ----IYDEAKSKGYLVLDHEGSS--DTQWWNSKPKDAAILDFTKTEVQEWFSKRLKRLQDEDGID 401
                .|||...:|..:.:..|..  ...|    |...|..|||..|..:|:...:.....:...|
  Rat   453 GSYRPYDEGLRRGVFITNETGQPLIGKVW----PGSTAFPDFTNPETLDWWQDMVSEFHAQVPFD 513

  Fly   402 SFKFDAGETS-------------------WLPS--DPVLQASSSMVTPLQAVGDYVRTVAAFG-- 443
            ....|..|.|                   ::|.  ...|||::...:..|.:..:......:|
  Rat   514 GMWIDMNEPSNFIRGSQQGCPDNELENPPYVPGVVGGALQAATICASSHQFLSTHYNLHNLYGLT 578

  Fly   444 -DMVEVRSAQNTQDQPIFVRIVDKDS---------EW------GWNNGLLTLISSMLQMNLNGYP 492
             .:...|:...|:....||  :.:.:         .|      .|.: |...:..:||.||.|.|
  Rat   579 EAIASSRALVKTRGTRPFV--ISRSTFAGHGRYAGHWTGDVWSSWEH-LAYSVPEILQFNLLGVP 640

  Fly   493 FVLPDMIGGNGYYEKPPTKELFLRWLQANVFMPALQ-------FSFVPWNFDDEA-IAISKNFTA 549
            .|..|:.|    ::...|:||.:||.|...|.|.::       ....|:.|.:.| .|:.|.||.
  Rat   641 LVGADICG----FQGNTTEELCVRWTQLGAFYPFMRNHNDLNSLPQEPYRFSETAQQAMRKAFTL 701

  Fly   550 LHATYTPYIMKLFKRAVDSGEPVNVPLWWIAPTDEVAQSIYDEFLLGEDIIAAPVVVEGATKRDI 614
            .:| ..||:..||..|...|:.|..||:...|.|....|:..:.|.|..::..||:..|.|....
  Rat   702 RYA-LLPYLYTLFHGAHVKGDTVARPLFLEFPEDPSTWSVDRQLLWGPALLITPVLEPGKTDVTG 765

  Fly   615 YLPEGEWQD---------GNSDQ----------VYTGPTWVMDYAAPLDTLPYFLRVGFTL 656
            |.|:|.|.:         |:...          |::...| :...|||||:...||.|:.:
  Rat   766 YFPKGMWYNLQMVPVETLGSLPSSSPASSFRSIVHSKGQW-LTLEAPLDTINVHLRAGYII 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tobi	NP_651391.1	GH31_NET37	255..621	CDD:269878	98/426 (23%)
Gaa	NP_954549.1	PD	81..132	CDD:197472
		NtCtMGAM_N	147..254	CDD:465286	1/3 (33%)
		GH31_N	246..359	CDD:270212	32/155 (21%)
		GH31_MGAM_SI_GAA	359..717	CDD:269888	84/379 (22%)