Protein Alignment tobi and Ganc

DIOPT Version :10

• Sequence 1: NP_651391.1
• Gene: tobi / 43072
• FlyBaseID: FBgn0261575
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_001139312.1
• Gene: Ganc / 24382
• RGDID: 2660
• Length: 913
• Species: Rattus norvegicus
• Alignment Length: 759
• Identity: 163/759 - (21%)
• Similarity: 269/759 - (35%)
• Gaps: 205/759 - (27%)

  Fly    25 IEQRYKFP---NSNV-YVRL-------------RRGD--------KLQYELMKGEKSLQTVT--- 61
            ::.||:.|   ||.: .|||             |:||        ..:.:|:..:::|.::.
  Rat    92 LKPRYEVPDVVNSKLGTVRLVCSGDTGSLTLTDRKGDLRCHISANPFKIDLLSKDEALISINSLG 156

  Fly    62 ---FDNFDSSANLVETSSGSYQLTDGQSTVEFTLVKSGVVAGTGSE----ITHVKVSRDQVLQGT 119
               |::.........|..      :||:|...|..::....|...|    ...|||:.
  Rat   157 KLYFEHLRVPHKQRATKG------NGQNTPADTFQENQEDLGLWEEKFGKFVDVKVNG------- 208

  Fly   120 QPRDCVPLKTG---STHWFSGPEQKQHYWPVERQRHSNYSYLPKELDNFGVGERYWLNGDGVFLY 181
                  |...|   |.|.|      :|.:.:.:...|:      :|.|...|:.|.|....|:.|
  Rat   209 ------PSSVGLDFSLHGF------EHLYGIPQHAESH------QLKNTRDGDAYRLYNLDVYGY 255

  Fly   182 -------VESNTPLFIDQNSAAYPDQLCLSAISALPYDPRVTSAKFVYHVAVAKDAKAAHRYAVK 239
                   :..:.|..:............|:|...|.......:|:  |.:.....|.|..:...:
  Rat   256 QVHDKMGIYGSVPYLLAHKQGRTVGIFWLNASETLVEINTEPAAE--YTLTQMGPAAAKQKVRCR 318

  Fly   240 T--------------FLGQPT--------GYPDERMVMHPVWS------TWALYKAEVSDDVVRD 276
            |              .|..||        .|......|.|::|      .|   ..|...||
  Rat   319 TNVHWMSESGIIDVFLLTGPTPADIFKQYSYITGTQAMPPLFSLGYHQCRW---NYEDEQDV--- 377

  Fly   277 FAKQILDNGFNNSQLEIDDDWEDCYGA-----MTFRKNKFPDSKTLTDDLKALGFRVTLWIHPFI 336
               :.:|.||:...:..|..|.|....     .|:.|.:|.:.|.:.:.|::.|.::.:...|.|
  Rat   378 ---KAVDAGFDEHDIPYDVMWLDIEHTEDKKYFTWDKKRFANPKRMQELLRSKGRKLVVISDPHI 439

  Fly   337 N-NNCTAIYDEAKSKGYLVLDHEGSS-DTQWWNSKPKDAAILDFTKTEVQEWFSKRLKRLQDEDG 399
            . :....:|.|||.:|:.|.:.||.. :...|   |..::.||||..:|:||:|          .
  Rat   440 KVDPDYTVYAEAKERGFFVKNPEGGDLEGVCW---PGLSSYLDFTNPKVREWYS----------S 491

  Fly   400 IDSFKFDAGETSWL-----PSDPVLQASSSMVTPLQAV--------------GDYVRTVAAFGDM 445
            :.:|....|.|..|     .::|.:.....:.....||              |.|.:...|.|
  Rat   492 LFAFPVYQGSTDILFLWNDMNEPSVFRGPELTMQKNAVHHGNWEHRELHNIYGFYHQMATAEG-- 554

  Fly   446 VEVRSAQNTQDQPIFVRIV-------------DKDSEWGWNNGLLTLISSMLQMNLNGYPFVLPD 497
             .::.:|..:...:..|..             |..:||.:   |...|..:|.::::|..|...|
  Rat   555 -LIQRSQGKERPFVLSRSFFAGSQKYGAVWTGDNTAEWSY---LKISIPMLLTLSVSGISFCGAD 615

  Fly   498 MIG--GNGYYEKPPTKELFLRWLQANVFMPALQFSFV-------PWNFDDEAIAISKNFTALHAT 553
            :.|  ||      |..||.:||.||..:.|..:....       ||.|..|...:.:.  |:...
  Rat   616 VGGFIGN------PEAELLVRWYQAAAYQPFFRGHATMNTKRREPWLFGAEYTQLIRE--AIRER 672

  Fly   554 YT--PYIMKLFKRAVDSGEPVNVPLWWIAPTDEVAQSIYDEFLLGEDIIAAPVVVEGATKRDIYL 616
            |:  ||:..||..|..|.:||..|||...|.|....::.||::||..::..||.....|..|::|
  Rat   673 YSLLPYLYSLFYHAHVSSQPVMRPLWVEFPDDLETFAVEDEYMLGNALLVHPVTAPQTTMIDVFL 737

  Fly   617 PEGEWQDGNSDQVYTGPT---W----VMDYAAPLDTLPYFLRVG 653
            |      |:::..|...|   |    .:.....|||:|.|.|.|
  Rat   738 P------GSNEVWYNSKTFAYWKGGCAVKVPVTLDTIPVFQRGG 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tobi	NP_651391.1	GH31_NET37	255..621	CDD:269878	101/421 (24%)
Ganc	NP_001139312.1	GH31_N	212..352	CDD:270212	26/153 (17%)
		GH31_GANC_GANAB_alpha	352..819	CDD:269889	112/466 (24%)