Protein Alignment tobi and aagr-1

DIOPT Version :10

• Sequence 1: NP_651391.1
• Gene: tobi / 43072
• FlyBaseID: FBgn0261575
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_501419.2
• Gene: aagr-1 / 177632
• WormBaseID: WBGene00017071
• Length: 936
• Species: Caenorhabditis elegans
• Alignment Length: 759
• Identity: 146/759 - (19%)
• Similarity: 228/759 - (30%)
• Gaps: 311/759 - (40%)

  Fly    71 LVETSSGSYQLTDGQSTVEFTLVKSGVVAGTGSEITHVKV-------------SRD--------- 113
            |.:||.|..|..|....:. |.:.|..:.|.|..| |.|:             :||
 Worm   164 LWDTSIGGMQFADKFIQIA-TYLPSKNIYGFGDHI-HKKIRHNLDRYTTWPMFARDIGPDSGSAL 226

  Fly   114 --QVLQGTQP------------------RDCVPLKTG-STH-------------WFSGPEQKQHY 144
              |.|.|..|                  .:...::|| ..|             :|.||..:|
 Worm   227 STQNLYGVHPFYMCIEADGKAHGVFILNSNAQEVETGPGPHLLYRTIGGRIDMAFFPGPTPEQ-- 289

  Fly   145 WPVERQ--RHSNYSYLPKELDNFGVGERYWLNGDGVFLYVESNTPLF---IDQNSAAYPDQLCLS 204
              |..|  :|..:.:||          .||..|..:..:...|....   |.:|.|.
 Worm   290 --VVNQYLQHIGFPFLP----------AYWALGYQLCRWGYGNLDAMKTVISRNQAL-------- 334

  Fly   205 AISALPYDPRVTSAKFVYHVAVAKDAKAAHRYAVKTFLGQPTGYPDERMVMHPVWSTWALYKAEV 269
               .:|.|.......::.|.   :|......:         :|:|.....:|    ...|:...:
 Worm   335 ---GIPLDVPYADIDYMNHY---EDFTEGDNW---------SGFPAYTQQIH----AQGLHLIVI 380

  Fly   270 SDDVVR-DFAKQILDNGFN--------------------------NSQLEIDDDWEDCYGAMTFR 307
            .|..|. |:|.  ...|.|                          |:::.:.:.|.|       |
 Worm   381 FDPAVEVDYAS--FQRGINADASFIEWARDDQVPHNIQDQYPMAKNTKIMLGNVWPD-------R 436

  Fly   308 KNKFPDSKTLTDDLKALGFRVTLWIHPFINNNCTAIYDEAKSKGYLVLDHEGSSDTQWW------ 366
            ...|||                 ::.|..|.|.                        ||
 Worm   437 NTAFPD-----------------FLDPRNNTNA------------------------WWAGEFAQ 460

  Fly   367 --NSKPKDAAILDFTKTEVQEWFSKRLKRLQDEDGIDSFKFDAGETSWLP--------SDPVLQA 421
              .:.|.|...:|..:..                     .||.|..:.:.        |.|:..:
 Worm   461 FHKTLPFDGMWIDMNEPS---------------------NFDTGTYNTVEEQLASAKLSCPITGS 504

  Fly   422 SSSMVT---PLQAV----GDYV--RTVAAFGDMVEVRSAQNTQDQPIFVRIVDKDSEWGWNNG-- 475
            .||:..   |.|||    |:|:  :|:...|     ::|..|:|      ..|..:.:||:..
 Worm   505 DSSLDVPPYPTQAVYQRNGEYLFSKTLCMLG-----KTAHRTRD------FYDTKNLYGWSEARA 558

  Fly   476 -----------------------------------------LLTLISSMLQMNLNGYPFVLPDMI 499
                                                     |.|.:..:::.|:.|.|:|..|:.
 Worm   559 TYQAIPQVTGKRSAVISRSTFPSSGRYGGHWLGDNTARWGDLQTSVIGVMEFNMFGVPYVGSDIC 623

  Fly   500 GGNGYYEKPPTKELFLRWLQANVFMPALQFS------FVP------WNFDDEAIAISKNFTALHA 552
            |.||.    ..:||.|||.|...|.|   ||      .:|      |.....|..|:..|   ..
 Worm   624 GFNGV----SNEELCLRWHQFGAFSP---FSRDHNSEGMPDQDPAVWPSVANAAKIALTF---RY 678

  Fly   553 TYTPYIMKLFKRAVDSGEPVNVPLWWIAPTDEVAQSIYDEFLLGEDIIAAPVVVEGATKRDIYLP 617
            .:.|::..|...|...|..|..||::..|.||...:|.::||.|..::.||.:.:|.|....|.|
 Worm   679 YFLPFLYSLHYNAARYGHTVIRPLFFEFPKDEETLNISEQFLWGSALMIAPALYQGQTSVHAYFP 743

  Fly   618 EGEW----QDGNSDQVYTGPTWVMDYAAPLDTL-PYFLRVGFTL 656
            ...|    .:....::::|   ..|..|||.:| |.|:|.||.|
 Worm   744 SDTWYSLQPETYGQKMFSG---FNDVNAPLSSLTPVFVRGGFVL 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tobi	NP_651391.1	GH31_NET37	255..621	CDD:269878	89/472 (19%)
aagr-1	NP_501419.2	PD	24..70	CDD:197472
		NtCtMGAM_N	85..187	CDD:465286	7/23 (30%)
		GH31_N	186..299	CDD:270212	22/117 (19%)
		GH31_MGAM_SI_GAA	299..691	CDD:269888	86/520 (17%)