Protein Alignment tobi and Gaa

DIOPT Version :9

• Sequence 1: NP_651391.1
• Gene: tobi / 43072
• FlyBaseID: FBgn0261575
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_001152796.1
• Gene: Gaa / 14387
• MGIID: 95609
• Length: 953
• Species: Mus musculus
• Alignment Length: 645
• Identity: 146/645 - (22%)
• Similarity: 230/645 - (35%)
• Gaps: 148/645 - (22%)

  Fly    91 TLVKSGVVAGTGSEITHVKVSRDQVLQGTQPRDCVPLKTGSTHWFSGPEQKQHYWPVERQRHSNY 155
            |.:.|..:.|.|..::.:.:|.|........|| .|...|:..:.|.|
Mouse   250 TSLPSQHITGLGEHLSPLMLSTDWARITLWNRD-TPPSQGTNLYGSHP----------------- 296

  Fly   156 SYLPKELDNFGVGERYWLNGDGVFLYVESNTPLFIDQNSAAYPDQLCLSAISALPYDPRVTSAKF 220
            .||  .|::.|:..       ||||.           ||.|.  .:.|....||.:  |.|....
Mouse   297 FYL--ALEDGGLAH-------GVFLL-----------NSNAM--DVILQPSPALTW--RSTGGIL 337

  Fly   221 VYHVAVAKDAKAAHRYAVKTFLGQPTGYPDERMVMHPVWS------TWALYKAEVSDDVVRDFAK 279
            ..:|.:..:.|:    .|:.:| ...|||    .|.|.|.      .|......:...||.:..:
Mouse   338 DVYVFLGPEPKS----VVQQYL-DVVGYP----FMPPYWGLGFHLCRWGYSSTAIVRQVVENMTR 393

  Fly   280 Q--ILDNGFNNSQLEIDDDWEDCYGAMTFRKNKFPDSKTLTDDLKALGFRVTLWIHPFINNNCTA 342
            .  .||..:|      |.|:.|.....||.::.|.|...:..:|...|.|..:.:.|.|::...|
Mouse   394 THFPLDVQWN------DLDYMDARRDFTFNQDSFADFPDMVRELHQDGRRYMMIVDPAISSAGPA 452

  Fly   343 ----IYDEAKSKGYLVLDHEGSS--DTQWWNSKPKDAAILDFTKTEVQEWFSKRLKRLQDEDGID 401
                .|||...:|..:.:..|..  ...|    |...|..|||..|..:|:...:.....:...|
Mouse   453 GSYRPYDEGLRRGVFITNETGQPLIGKVW----PGTTAFPDFTNPETLDWWQDMVSEFHAQVPFD 513

  Fly   402 SFKFDAGETS-------------------WLPS--DPVLQASSSMVTPLQAVGDYVRTVAAFG-- 443
            ....|..|.|                   ::|.  ..:|||::...:..|.:..:......:|
Mouse   514 GMWLDMNEPSNFVRGSQQGCPNNELENPPYVPGVVGGILQAATICASSHQFLSTHYNLHNLYGLT 578

  Fly   444 -DMVEVRSAQNTQDQPIFVRIVDKDS---------EW------GWNNGLLTLISSMLQMNLNGYP 492
             .:...|:...|:....||  :.:.:         .|      .|.: |...:..:||.||.|.|
Mouse   579 EAIASSRALVKTRGTRPFV--ISRSTFSGHGRYAGHWTGDVRSSWEH-LAYSVPDILQFNLLGVP 640

  Fly   493 FVLPDMIGGNGYYEKPPTKELFLRWLQANVFMPALQ----FSFV---PWNFDDEAIAISKNFTAL 550
            .|..|:.|..|    ..::||.:||.|...|.|.::    .:.|   |:.|.:.|....:...||
Mouse   641 LVGADICGFIG----DTSEELCVRWTQLGAFYPFMRNHNDLNSVPQEPYRFSETAQQAMRKAFAL 701

  Fly   551 HATYTPYIMKLFKRAVDSGEPVNVPLWWIAPTDEVAQSIYDEFLLGEDIIAAPVVVEGATKRDIY 615
            .....||:..||.||...|:.|..||:...|.|....|:..:.|.|..::..||:..|.|:...|
Mouse   702 RYALLPYLYTLFHRAHVRGDTVARPLFLEFPEDPSTWSVDRQLLWGPALLITPVLEPGKTEVTGY 766

  Fly   616 LPEGEW---QDGNSDQVYTGPT----------------WVMDYAAPLDTLPYFLRVGFTL 656
            .|:|.|   |..:.|.:.|.|:                | :...|||||:...||.|:.:
Mouse   767 FPKGTWYNMQMVSVDSLGTLPSPSSASSFRSAVQSKGQW-LTLEAPLDTINVHLREGYII 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tobi	NP_651391.1	Glyco_hydro_31	246..653	CDD:279404	113/485 (23%)
		GH31_NET37	255..621	CDD:269878	97/425 (23%)
Gaa	NP_001152796.1	Trefoil	82..130	CDD:278515
		NtCtMGAM_N	147..253	CDD:293468	1/2 (50%)
		GH31_N	246..359	CDD:270212	32/155 (21%)
		Glyco_hydro_31	340..825	CDD:279404	118/511 (23%)
		GH31_MGAM_SI_GAA	359..717	CDD:269888	83/378 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838260
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1501
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740