Protein Alignment rha and LOC11175542

DIOPT Version :10

• Sequence 1: NP_651390.2
• Gene: rha / 43071
• FlyBaseID: FBgn0027376
• Length: 1332
• Species: Drosophila melanogaster
• Sequence 2: XP_061500726.1
• Gene: LOC11175542 / 11175542
• VectorBaseID: AGAMI1_007591
• Length: 868
• Species: Anopheles gambiae
• Alignment Length: 1356
• Identity: 241/1356 - (17%)
• Similarity: 418/1356 - (30%)
• Gaps: 571/1356 - (42%)

  Fly    28 KDSDQVYCVLLHVVEAINFIGRDATDRQQIVMNAALNSVDFEVEG----TQSEETIIFNSNCIWE 88
            ||.:|...:.:.|:..|:|  ::....::|.:.|:||...||...    |....|..|:...:|:
Mosquito     6 KDDEQQLVIFVQVLGGIHF--QEEKQGRKIALTASLNQQVFEAVSRRPVTPGSGTASFDVKLVWQ 68

  Fly    89 CDLAGIKRLKTDHRPVKMTFYACRGGGAERKTIGTLLLPVRGLPVLGTVGSHNSPHLKMFWHKLI 153
            ||...:|.:||.:.|:|:..|..:..|. |..||::::|:|.:||: |:....:  :|..|::|:
Mosquito    69 CDRYTLKSIKTKNTPIKLDCYEVQPSGV-RSPIGSVVIPLRSVPVV-TLSRIKT--IKPRWYRLV 129

  Fly   154 CTSSE-FRSHKPEVLLMLTIIKKSILHTKDFEHFMQFTEVKSPPTPPMQSPGHSITASMLQSQA- 216
            ...:| :|..|||:.|::.:        .|.:|..|........||.:......:..|..:.:.
Mosquito   130 GIENERWRRIKPELKLLVMV--------ADSQHLDQCQARDDSSTPDLSGDELLMKRSAPKPETL 186

  Fly   217 --NVYVQSLVQLGLLQVG-NDPLVDCDIIEVVLQLKQLRNVTGLVKSLNQGKPPSSVI-LVFDFV 277
              |  |:.|...|||||| .|...|..:.|:||:..|         .|::..|.:... |.::..
Mosquito   187 PRN--VELLEDRGLLQVGCKDTETDLFVFEIVLKCAQ---------HLDRLCPGTDTFRLQYELF 240

  Fly   278 G--NVTNIELKLNESDTYTLNDVLGLRFKTSLRSMRLYFQRIFYLPINMYMNGTAIAHYRMDFTN 340
            |  :|:..|...:.|..:.:...:.:..::|:.::..||...|.:.|.:...|
Mosquito   241 GERHVSMAERTKSGSPVFDVKAKIRINLRSSILTLVDYFDNGFKIAIMVLTGG------------ 293

  Fly   341 LLPADDFFSDNRKYTSNGSFSFNRFGRTDSGREPKPPLMEYTFSVDLKTIFSRQEQEEPERTPSI 405
                                                                  |:|..|||  :
Mosquito   294 ------------------------------------------------------EEEIRERT--V 302

  Fly   406 ASGNLDSEDEQYLGQTFCASVVRSRLNLNESEETDEIASNVMKQLANDSETEVIEMKSNTKNSKH 470
            .:..:|     ::|          .|..|...|..|      ...||....|.:      ::...
Mosquito   303 GTTTID-----FVG----------FLKTNHVREFKE------NHPANSYTLEAV------RSLPV 340

  Fly   471 NTSPQRKSQESKKLIRESSRNTRNSLENLQNVDELTSLDLFELEEKRQEKIAELERIKAGQSESL 535
            :|:..||                               ||.::||
Mosquito   341 HTTTTRK-------------------------------DLNQIEE-------------------- 354

  Fly   536 LQTELKVKKHKKADLELQGKKSQLETINEVPPKSLRKSKPVSQSELNNVPKIQENLPILNNQTKG 600
            :...||:|      |.|               :.|...:||:         ::::|    ...|.
Mosquito   355 IVPSLKIK------LSL---------------RCLGSDRPVA---------VEKHL----EAAKE 385

  Fly   601 SRIQKENCEENNEDLSYALSEEHSSSNEKLDKKPGASKTM-RPPEHVDTDLETDISVFSIQKKRK 664
            |.|.::|.              ||:|.|.:.|.....|.: :||..|
Mosquito   386 SSIPEQNA--------------HSASTEPITKPDSLPKQLSKPPTPV------------------ 418

  Fly   665 SKSKLVISNELHNFEDSSTDTLEKGRPNPSKGDLKLRARWVEVNKVQTQALIETEKFLQKTCPAE 729
                              ||       ||.                               |.||
Mosquito   419 ------------------TD-------NPH-------------------------------CDAE 427

  Fly   730 LDEVLYEDQVALGQAKTSKPTKRKVKKPEEDKVKRIDYETSYEEEITFCHPEKDPMTMIGENPIN 794
            .:::                           .::||...|..                      |
Mosquito   428 REKI---------------------------DIERILLTTEQ----------------------N 443

  Fly   795 LNDLASSEEY---ISISEGNSKPAEIVYTETEQRVTFVNPKRDREKKKLSSLSKDDLLVEVRSEE 856
            |.|:..:..:   :......|.||..::     ::...:||.|....|:    :.:||.:|
Mosquito   444 LRDIRHTFAFRVCVGTVRFTSGPASGLW-----QLALQHPKADTPFTKV----RLELLPDV---- 495

  Fly   857 YINLRSSARSKTDCVRKKKKISIHEDQV----YQAELTPSEEPSSQSESRGTDNANPITDQPQVD 917
                                 ::|||::    ...||..|..|                     |
Mosquito   496 ---------------------AVHEDRIEFGGVTLELFFSTLP---------------------D 518

  Fly   918 RVKKKKRDTSGDQQLFHVEYTSSQKSISKTEGNVKCKELIEPDVEQTDVQVLKKKKLKKTLVTND 982
            :|               |:...|:.|.....|......|...|.|...|...:::.....::.|:
Mosquito   519 KV---------------VDIIGSEPSKLTLNGPHSTYALARLDNESLLVGTRERQPAGVVVMINE 568

  Fly   983 -----TVAQDYETLEEETIKPVKKKIVRKKSSVILEKIEDTENKGPADEVVSVEAKKIIKKKAKP 1042
                 .:|....||||..:.      ...:..|:.|  |.|.                     :.
Mosquito   569 AGENVAIASISCTLEEVGLN------YNSQMGVVQE--EPTR---------------------QD 604

  Fly  1043 ACDNPTVEEYPKTKKGESRKLKSTSKEHFTMEKPSSTIDSIGQKIKSWRRQQIDLFEQELARKEM 1107
            .|.:..    |:|..|.:::..:|            ....:.:|.|:|..:|...|.::|..||.
Mosquito   605 CCHSAA----PQTAHGLAKRFDAT------------VAYQLVEKQKAWMHEQRQQFMEQLEEKER 653

  Fly  1108 HYIKQLEQ------------MESQEARLHQL--------HKADTNLDETFISKIPNVSEVD--YE 1150
            .:::.|||            :..:.||...|        .||:|.:.|..    |.|.:::  ::
Mosquito   654 KHLQALEQSWKKRQAETEKRLADRLARADALAAALEEANRKAETRVPEDG----PRVKQIEQQFK 714

  Fly  1151 AKFTELEEHIALLKSEMEEQVRLFENRSRELRQENLQ--------------LYSEKTELKVRIAA 1201
            |:..|:......|:.|.|.|:.....:.|||:|:..|              |.||..:.:...||
Mosquito   715 AQLEEIRAKAVRLEQEAEAQIETTRRQCRELQQQQAQLSISQQQLLDSNRTLQSELDQERASRAA 779

  Fly  1202 LEQQIGDLKAQGSDEGDLKEVLGELRSQHYRYNNLAREKELFRKRWRRSAKRVHALKLAMYERSL 1266
            ||||:              |.:.|.: |||        |||    |.:..::||.|:   .|.|:
Mosquito   780 LEQQL--------------EEMAESK-QHY--------KEL----WAKLTRKVHQLQ---EELSM 814

  Fly  1267 EREHSNIRVEPIDLRKILTKDAEEFEREYGQFRQNGMS-----PRYTLNSLSGSGD 1317
            .|. ...:..|       .|||.:..|:......:.||     ||      .|:||
Mosquito   815 ART-PYFQAAP-------AKDARKGRRKIAASSSSQMSVARGGPR------QGAGD 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rha	NP_651390.2	DUF3668	158..387	CDD:463569	40/236 (17%)
		PTZ00108	<473..775	CDD:240271	38/302 (13%)
		COG4913	<1092..>1307	CDD:443941	60/255 (24%)
LOC11175542	XP_061500726.1	None