Protein Alignment CG11902 and ZBTB48

DIOPT Version :10

• Sequence 1: NP_651389.3
• Gene: CG11902 / 43070
• FlyBaseID: FBgn0028647
• Length: 1426
• Species: Drosophila melanogaster
• Sequence 2: NP_005332.1
• Gene: ZBTB48 / 3104
• HGNCID: 4930
• Length: 688
• Species: Homo sapiens
• Alignment Length: 602
• Identity: 130/602 - (21%)
• Similarity: 191/602 - (31%)
• Gaps: 221/602 - (36%)

  Fly   839 GLELNLESSETDTESEQEDNHSSLNYPCNLCTTVVKRKH----------------QLYAHQLEEH 887
            |.:|...|:|.:...:.||:... :|.......:.:||.                .|.|...|..
Human   221 GAQLQGGSNEWEVVVQVEDDGDG-DYMSEPEAVLTRRKSNVIRKPCAAEPALSAGSLAAEPAENR 284

  Fly   888 KWEEAVLVCSNCQTRFVNESLLDHHSRTLCHNPQKLFQCRKCPLRFRWRENLKLHMEVFHMLDEL 952
            |.....:.|..|..:|:::..|..|:|.  |..:|.|:|.||...:..:|||..|
Human   285 KGTAVPVECPTCHKKFLSKYYLKVHNRK--HTGEKPFECPKCGKCYFRKENLLEH---------- 337

  Fly   953 SIQDDLPKVDGDLQCGKC-NRSFRMQKDLTRHTLMHGQESNIFRCRWCARRFYRRANLLQHIARH 1016
                         :...| |||                 ..:|.|..|...|.||..|..|:..|
Human   338 -------------EARNCMNRS-----------------EQVFTCSVCQETFRRRMELRVHMVSH 372

  Fly  1017 GISVSQLPYAEAILDSYVNPGGRKKVECRVCNVSFPTIAALRLHLETMPAGSHHDYSSLQNYSIT 1081
               ..::||                 :|..|:..|.....|:.|:
Human   373 ---TGEMPY-----------------KCSSCSQQFMQKKDLQSHM-------------------- 397

  Fly  1082 NQMGFEMDLYDSETDDEDSRTHIKPPGAPSSYTCNMCQLRCLRKFELYQHQQAMHRMEKISDGCD 1146
                                  ||..|||..:.|..|....|.:.||..|:...||.||:
Human   398 ----------------------IKLHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKL----- 435

  Fly  1147 SCLFKSVCPEIISHHKRTQCENREKQFKCTRCGYKFMWESNLLLHMDLQHVKTEDQELDESKEAS 1211
                                      |.|..||::....:.|.:|:..:|
Human   436 --------------------------FVCEECGHRASSRNGLQMHIKAKH--------------- 459

  Fly  1212 GDEPKTEGQVFQCGLCTRKYNRKDRLTAHLKKFHGPDCKPSTAKTPNRPISPKEPKRFLCAFCGK 1276
                                 |.:|                    |:           :|.||..
Human   460 ---------------------RNER--------------------PH-----------VCEFCSH 472

  Fly  1277 AVSSSSNLIIHMRRHTGEKPFKCEYCTMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQ 1341
            |.:..:||.:|:|.|||||||:|..|...|...:.|..|.||||||||..|..|::.|.....|.
Human   473 AFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGERPFSCEFCEQRFTEKGPLL 537

  Fly  1342 QHMRI-HSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRMQQSH 1405
            :|:.. |...||:.|..|.|:|.....|.:|:|||.|.|.::|..||.:|.:...|:.|......
Human   538 RHVASRHQEGRPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDR 602

  Fly  1406 YEEGQESVEPTRRTVLE 1422
            .|.........|..::|
Human   603 VENYNPRQRKLRNLIIE 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11902	NP_651389.3	zf-AD	6..83	CDD:462262
		C2H2 Zn finger	208..228	CDD:275370
		C2H2 Zn finger	236..256	CDD:275370
		C2H2 Zn finger	384..405	CDD:275368
		C2H2 Zn finger	417..437	CDD:275368
		C2H2 Zn finger	447..463	CDD:275368
		C2H2 Zn finger	578..599	CDD:275368
		C2H2 Zn finger	610..629	CDD:275368
		C2H2 Zn finger	640..660	CDD:275368
		SUF4-like	673..>726	CDD:411020
		C2H2 Zn finger	676..703	CDD:411020
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	706..726	CDD:411020
		C2H2 Zn finger	706..726	CDD:275368
		C2H2 Zn finger	762..782	CDD:275368
		C2H2 Zn finger	866..887	CDD:275368	5/36 (14%)
		C2H2 Zn finger	896..918	CDD:275368	6/21 (29%)
		C2H2 Zn finger	926..947	CDD:275368	7/20 (35%)
		C2H2 Zn finger	967..987	CDD:275368	4/20 (20%)
		C2H2 Zn finger	996..1016	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1044..1063	CDD:275368	5/18 (28%)
		C2H2 Zn finger	1224..1244	CDD:275368	2/19 (11%)
		C2H2 Zn finger	1271..1291	CDD:275368	8/19 (42%)
		zf-H2C2_2	1283..1306	CDD:463886	13/22 (59%)
		C2H2 Zn finger	1299..1319	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1327..1347	CDD:275368	5/20 (25%)
		zf-H2C2_2	1340..1364	CDD:463886	9/24 (38%)
		SFP1	<1349..1405	CDD:227516	19/55 (35%)
		C2H2 Zn finger	1355..1375	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1383..1401	CDD:275368	6/17 (35%)
ZBTB48	NP_005332.1	BTB_POZ_ZBTB48_TZAP_KR3	8..115	CDD:349541
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	119..140
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..192
		C2H2 Zn finger	293..313	CDD:275368	6/21 (29%)
		zf-H2C2_2	305..328	CDD:463886	9/24 (38%)
		C2H2 Zn finger	321..372	CDD:275368	19/90 (21%)
		SFP1	<374..459	CDD:227516	28/174 (16%)
		C2H2 Zn finger	380..401	CDD:275368	7/62 (11%)
		C2H2 Zn finger	409..425	CDD:275370	5/15 (33%)
		C2H2 Zn finger	438..459	CDD:275368	5/20 (25%)
		COG5048	<464..612	CDD:227381	55/158 (35%)
		C2H2 Zn finger	467..487	CDD:275368	8/19 (42%)
		C2H2 Zn finger	495..515	CDD:275368	6/19 (32%)
		C2H2 Zn finger	523..540	CDD:275368	4/16 (25%)
		C2H2 Zn finger	555..572	CDD:275368	6/16 (38%)
		C2H2 Zn finger	580..600	CDD:275368	6/19 (32%)