Protein Alignment CG11902 and Zic3

DIOPT Version :10

• Sequence 1: NP_651389.3
• Gene: CG11902 / 43070
• FlyBaseID: FBgn0028647
• Length: 1426
• Species: Drosophila melanogaster
• Sequence 2: NP_033601.2
• Gene: Zic3 / 22773
• MGIID: 106676
• Length: 466
• Species: Mus musculus
• Alignment Length: 182
• Identity: 58/182 - (31%)
• Similarity: 87/182 - (47%)
• Gaps: 36/182 - (19%)

  Fly  1208 KEASGDEPKTEGQVFQCGLCTRKYNRKDRLTAHLKKFH--GPDCKPSTAKTPNRPI-----SPKE 1265
            :||....||..        |.|.::....|..|:...|  ||:        .|..:     .|:|
Mouse   256 EEAQLSRPKKS--------CDRTFSTMHELVTHVTMEHVGGPE--------QNNHVCYWEECPRE 304

  Fly  1266 PKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEY--CTMAFPRSSDLQCHRRTHTGERPHVCT 1328
                     ||:..:...|:.|:|.|||||||.|.:  |...|.||.:|:.|:||||||:|..|.
Mouse   305 ---------GKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCE 360

  Fly  1329 V--CQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGE 1378
            .  |.:.||.|...::||.:|:.::||.|..|:||:|..:.|..|::.|..:
Mouse   361 FEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKVHESQ 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11902	NP_651389.3	zf-AD	6..83	CDD:462262
		C2H2 Zn finger	208..228	CDD:275370
		C2H2 Zn finger	236..256	CDD:275370
		C2H2 Zn finger	384..405	CDD:275368
		C2H2 Zn finger	417..437	CDD:275368
		C2H2 Zn finger	447..463	CDD:275368
		C2H2 Zn finger	578..599	CDD:275368
		C2H2 Zn finger	610..629	CDD:275368
		C2H2 Zn finger	640..660	CDD:275368
		SUF4-like	673..>726	CDD:411020
		C2H2 Zn finger	676..703	CDD:411020
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	706..726	CDD:411020
		C2H2 Zn finger	706..726	CDD:275368
		C2H2 Zn finger	762..782	CDD:275368
		C2H2 Zn finger	866..887	CDD:275368
		C2H2 Zn finger	896..918	CDD:275368
		C2H2 Zn finger	926..947	CDD:275368
		C2H2 Zn finger	967..987	CDD:275368
		C2H2 Zn finger	996..1016	CDD:275368
		C2H2 Zn finger	1044..1063	CDD:275368
		C2H2 Zn finger	1224..1244	CDD:275368	4/19 (21%)
		C2H2 Zn finger	1271..1291	CDD:275368	5/19 (26%)
		zf-H2C2_2	1283..1306	CDD:463886	12/24 (50%)
		C2H2 Zn finger	1299..1319	CDD:275368	8/21 (38%)
		C2H2 Zn finger	1327..1347	CDD:275368	7/21 (33%)
		zf-H2C2_2	1340..1364	CDD:463886	9/23 (39%)
		SFP1	<1349..1405	CDD:227516	10/30 (33%)
		C2H2 Zn finger	1355..1375	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1383..1401	CDD:275368
Zic3	NP_033601.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..103
		zf_ZIC	244..289	CDD:436441	9/40 (23%)
		Nuclear localization signal. /evidence=ECO:0000250	296..321		7/33 (21%)
		C2H2 Zn finger	301..321	CDD:275368	7/28 (25%)
		SFP1	<323..407	CDD:227516	36/83 (43%)
		C2H2 Zn finger	329..351	CDD:275368	8/21 (38%)
		Nuclear localization signal. /evidence=ECO:0000250	329..351		8/21 (38%)
		C2H2 Zn finger	359..381	CDD:275368	7/21 (33%)
		C2H2 Zn finger	389..409	CDD:275368	7/19 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	403..466		2/10 (20%)