Protein Alignment CG11902 and GLIS3

DIOPT Version :10

• Sequence 1: NP_651389.3
• Gene: CG11902 / 43070
• FlyBaseID: FBgn0028647
• Length: 1426
• Species: Drosophila melanogaster
• Sequence 2: NP_001035878.1
• Gene: GLIS3 / 169792
• HGNCID: 28510
• Length: 930
• Species: Homo sapiens
• Alignment Length: 208
• Identity: 64/208 - (30%)
• Similarity: 97/208 - (46%)
• Gaps: 39/208 - (18%)

  Fly  1189 LLHMDL----QHVKTEDQELDESKEASGDEPKTEGQVFQCGL---CTRKYNRKDRLTAHLKKFHG 1246
            |.|.:|    |.:......||:..|..|...|      .|..   |:..|::::.|..|::|.|
Human   468 LHHPELGPHAQQLALPQATLDDDGEMDGIGGK------HCCRWIDCSALYDQQEELVRHIEKVH- 525

  Fly  1247 PDCKPSTAKTPNRPISPKEPKRFLCAFCG-----KAVSSSSNLIIHMRRHTGEKPFKC--EYCTM 1304
                          |..::.:.|.|.:.|     |..::...|:||||.|:||||.||  |.|..
Human   526 --------------IDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEK 576

  Fly  1305 AFPRSSDLQCHRRTHTGERPHVC--TVCQKGFARSYKLQQHMRIHSGERPYKCTY--CEKSFTQS 1365
            ||.|..:|:.|.|:||||:|::|  ..|||.|:.|....:|.|.|...:||.|..  |.|.:|..
Human   577 AFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDP 641

  Fly  1366 NDLTLHIRRHTGE 1378
            :.|..|::.|:.:
Human   642 SSLRKHVKAHSSK 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11902	NP_651389.3	zf-AD	6..83	CDD:462262
		C2H2 Zn finger	208..228	CDD:275370
		C2H2 Zn finger	236..256	CDD:275370
		C2H2 Zn finger	384..405	CDD:275368
		C2H2 Zn finger	417..437	CDD:275368
		C2H2 Zn finger	447..463	CDD:275368
		C2H2 Zn finger	578..599	CDD:275368
		C2H2 Zn finger	610..629	CDD:275368
		C2H2 Zn finger	640..660	CDD:275368
		SUF4-like	673..>726	CDD:411020
		C2H2 Zn finger	676..703	CDD:411020
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	706..726	CDD:411020
		C2H2 Zn finger	706..726	CDD:275368
		C2H2 Zn finger	762..782	CDD:275368
		C2H2 Zn finger	866..887	CDD:275368
		C2H2 Zn finger	896..918	CDD:275368
		C2H2 Zn finger	926..947	CDD:275368
		C2H2 Zn finger	967..987	CDD:275368
		C2H2 Zn finger	996..1016	CDD:275368
		C2H2 Zn finger	1044..1063	CDD:275368
		C2H2 Zn finger	1224..1244	CDD:275368	5/22 (23%)
		C2H2 Zn finger	1271..1291	CDD:275368	8/24 (33%)
		zf-H2C2_2	1283..1306	CDD:463886	14/24 (58%)
		C2H2 Zn finger	1299..1319	CDD:275368	9/21 (43%)
		C2H2 Zn finger	1327..1347	CDD:275368	8/21 (38%)
		zf-H2C2_2	1340..1364	CDD:463886	8/25 (32%)
		SFP1	<1349..1405	CDD:227516	9/32 (28%)
		C2H2 Zn finger	1355..1375	CDD:275368	6/21 (29%)
		C2H2 Zn finger	1383..1401	CDD:275368
GLIS3	NP_001035878.1	SFP1	<558..652	CDD:227516	39/93 (42%)
		C2H2 Zn finger	569..591	CDD:275368	9/21 (43%)
		C2H2 Zn finger	599..621	CDD:275368	8/21 (38%)
		C2H2 Zn finger	629..651	CDD:275368	6/21 (29%)