Protein Alignment CG10669 and ZNF668

DIOPT Version :10

• Sequence 1: NP_651388.1
• Gene: CG10669 / 43069
• FlyBaseID: FBgn0039329
• Length: 933
• Species: Drosophila melanogaster
• Sequence 2: NP_001166140.1
• Gene: ZNF668 / 79759
• HGNCID: 25821
• Length: 642
• Species: Homo sapiens
• Alignment Length: 594
• Identity: 126/594 - (21%)
• Similarity: 182/594 - (30%)
• Gaps: 222/594 - (37%)

  Fly   348 SASASAPTAKPSRINRRVDGFDFHRSEPNGAKEIKCMICLRRFTKLRELRNHLQNH-PTDFDFEA 411
            :|.|.:|.....|..||                .||:.|.:.|........|...| |.|..
Human    28 AAEARSPAPGYKRSGRR----------------YKCLSCTKTFPNAPRAARHAATHGPADCS--- 73

  Fly   412 HGEPIERIAEGFFKTAVESTAEGLKRRIFRDLRMGVYGRYYSITNQARYEMTLDSSDTDSDGDGD 476
                 |.:||...|...|:.||                               ::|.....|
Human    74 -----EEVAEVKPKPETEAKAE-------------------------------EASGEKVSG--- 99

  Fly   477 DNVVIRRSYSCELC-----DSPEARWPRKYLLHQHHQKEHTWLDAPHVCQRCDSRFLNLQLLK-- 534
             :....|.|:|.||     .:||.|         .|.:.||. :.|..|..|..||:....|:
Human   100 -SAAKPRPYACPLCPKAYKTAPELR---------SHGRSHTG-EKPFPCPECGRRFMQPVCLRVH 153

  Fly   535 --HHTSQLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKCKQESYPCDQCSRSFQDKSAVTKHKL 597
              .|..:|      .|.|..||:.:.....|:.|...| ..:..|.|..|.:||.|
Human   154 LASHAGEL------PFRCAHCPKAYGALSKLKIHQRGH-TGERPYACADCGKSFAD--------- 202

  Fly   598 MMHRDSNMELLPCRWCTRTFYRPALLYKHLQRHGFTGQDLPLAETLLADASKPAGPKSVQCKICD 662
                                  |::..||.:.|                    ||.:...|:.|.
Human   203 ----------------------PSVFRKHRRTH--------------------AGLRPYSCERCG 225

  Fly   663 IQFVSVADLRRHISMQGHSDQPSAYMISTATGFELLLDDTDDSDEETSGRTYSCDLCDLNFRRRR 727
            ..:..:.|||.|                              ....|..|.:.|..|..:|.|..
Human   226 KAYAELKDLRNH------------------------------ERSHTGERPFLCSECGKSFSRSS 260

  Fly   728 EISEHQYSLHSFDKLPHNCEHCIFKTVDKNMLHQHLRTQCMNTEKKFACMRCGYKFMWEENLAQH 792
            .::.|| .:|:                               .:|.:.|..||..|....:...|
Human   261 SLTCHQ-RIHA-------------------------------AQKPYRCPACGKGFTQLSSYQSH 293

  Fly   793 LSTQHSKQPAVPEQQPPLRRKRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPG-KKYLCSLC 856
            ..|...::|                :.||.|.|.|....|..:|.|      .:.| |.|.|..|
Human   294 ERTHSGEKP----------------FLCPRCGRMFSDPSSFRRHQR------AHEGVKPYHCEKC 336

  Fly   857 GLESLTPNKLNIHMRRHTGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCDKDFARPDK 921
            |.:...|..|.:|.|.|||::||||..||..|...::||.|...|:|:||::|..|.:.||....
Human   337 GKDFRQPADLAMHRRVHTGDRPFKCLQCDKTFVASWDLKRHALVHSGQRPFRCEECGRAFAERAS 401

  Fly   922 LRRHVFMHN 930
            |.:|..:|:
Human   402 LTKHSRVHS 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10669	NP_651388.1	zf-AD	4..80	CDD:462262
		C2H2 Zn finger	178..199	CDD:275368
		C2H2 Zn finger	216..233	CDD:275368
		C2H2 Zn finger	520..542	CDD:275368	7/25 (28%)
		C2H2 Zn finger	550..570	CDD:275368	5/19 (26%)
		C2H2 Zn finger	579..600	CDD:275368	5/20 (25%)
		C2H2 Zn finger	610..630	CDD:275368	3/19 (16%)
		C2H2 Zn finger	716..737	CDD:275368	6/20 (30%)
		C2H2 Zn finger	746..766	CDD:275368	0/19 (0%)
		C2H2 Zn finger	776..795	CDD:275368	5/18 (28%)
		C2H2 Zn finger	820..838	CDD:275368	7/17 (41%)
		C2H2 Zn finger	853..873	CDD:275368	7/19 (37%)
		zf-H2C2_2	866..889	CDD:463886	12/22 (55%)
		C2H2 Zn finger	881..901	CDD:275368	7/19 (37%)
		zf-H2C2_2	893..918	CDD:463886	10/24 (42%)
		C2H2 Zn finger	909..929	CDD:275368	6/19 (32%)
ZNF668	NP_001166140.1	COG5048	103..437	CDD:227381	103/460 (22%)
		C2H2 Zn finger	109..129	CDD:275370	7/28 (25%)
		C2H2 Zn finger	137..157	CDD:275368	5/19 (26%)
		C2H2 Zn finger	165..185	CDD:275368	5/19 (26%)
		C2H2 Zn finger	193..213	CDD:275368	8/50 (16%)
		C2H2 Zn finger	221..241	CDD:275368	6/49 (12%)
		C2H2 Zn finger	249..269	CDD:275368	6/20 (30%)
		COG5048	271..618	CDD:227381	50/162 (31%)
		C2H2 Zn finger	277..297	CDD:275368	5/19 (26%)
		C2H2 Zn finger	305..325	CDD:275368	8/25 (32%)
		C2H2 Zn finger	333..353	CDD:275368	7/19 (37%)
		C2H2 Zn finger	361..381	CDD:275368	7/19 (37%)
		C2H2 Zn finger	389..409	CDD:275368	6/19 (32%)
		C2H2 Zn finger	417..437	CDD:275368
		C2H2 Zn finger	541..561	CDD:275368
		C2H2 Zn finger	569..589	CDD:275368
		C2H2 Zn finger	597..617	CDD:275368