DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10669 and che-1

DIOPT Version :9

Sequence 1:	NP_001163728.1	Gene:	CG10669 / 43069	FlyBaseID:	FBgn0039329	Length:	933	Species:	Drosophila melanogaster
Sequence 2:	NP_001076598.1	Gene:	che-1 / 183847	WormBaseID:	WBGene00000483	Length:	273	Species:	Caenorhabditis elegans

Alignment Length:	159	Identity:	45/159 - (28%)
Similarity:	73/159 - (45%)	Gaps:	24/159 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   790 AQHLSTQHSKQ------------PA--VPEQQP-----PLRRKRRFRYQCPHCWRSFVVQPSLDK 835
            :.|::|...:|            |:  :|:::|     |:.|.....::|..|.::|....:|..
Worm   119 SNHITTDSFRQIPPSGLCYMDPTPSLRLPKKEPLPVQRPMARSTPKPFRCQTCGKAFSQAANLTA 183

  Fly   836 HIRDMHVAKKNPGKKYLCSLCGLESLTPNKLNIHMRRHTGEKPFKCDLCDMRFTVHYELKVHRRK 900
            |.| :|..:    |.::|.:|.......:.|..|.|.||||:|:.|..|:..||....|..|.|.
Worm   184 HKR-IHTGE----KPFMCPVCNRPFSQSSSLVTHRRTHTGERPYPCAQCEKAFTDSSTLTKHLRT 243

  Fly   901 HTGERPYQCTFCDKDFARPDKLRRHVFMH 929
            |||.:||.|:.|...|.:...|.||:..|
Worm   244 HTGHKPYVCSICMMKFTQSGNLHRHMKTH 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10669	NP_001163728.1	zf-AD	4..81	CDD:285071
		C2H2 Zn finger	178..199	CDD:275368
		C2H2 Zn finger	216..233	CDD:275368
		C2H2 Zn finger	520..542	CDD:275368
		C2H2 Zn finger	550..570	CDD:275368
		C2H2 Zn finger	579..600	CDD:275368
		C2H2 Zn finger	610..630	CDD:275368
		C2H2 Zn finger	716..737	CDD:275368
		C2H2 Zn finger	746..766	CDD:275368
		C2H2 Zn finger	776..795	CDD:275368	1/4 (25%)
		C2H2 Zn finger	820..838	CDD:275368	5/17 (29%)
		C2H2 Zn finger	853..873	CDD:275368	5/19 (26%)
		zf-H2C2_2	866..889	CDD:290200	10/22 (45%)
		COG5048	877..>930	CDD:227381	20/53 (38%)
		C2H2 Zn finger	881..901	CDD:275368	7/19 (37%)
		zf-H2C2_2	893..918	CDD:290200	11/24 (46%)
		C2H2 Zn finger	909..929	CDD:275368	6/19 (32%)
che-1	NP_001076598.1	zf-C2H2	166..188	CDD:278523	6/22 (27%)
		C2H2 Zn finger	168..188	CDD:275368	6/20 (30%)
		zf-H2C2_2	180..205	CDD:290200	7/29 (24%)
		C2H2 Zn finger	196..216	CDD:275368	5/19 (26%)
		zf-H2C2_2	208..232	CDD:290200	10/23 (43%)
		C2H2 Zn finger	224..244	CDD:275368	7/19 (37%)
		zf-H2C2_2	237..261	CDD:290200	11/23 (48%)
		C2H2 Zn finger	252..272	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000