Protein Alignment CG10669 and Znf48

DIOPT Version :10

• Sequence 1: NP_651388.1
• Gene: CG10669 / 43069
• FlyBaseID: FBgn0039329
• Length: 933
• Species: Drosophila melanogaster
• Sequence 2: NP_001388702.1
• Gene: Znf48 / 103690203
• RGDID: 9115869
• Length: 590
• Species: Rattus norvegicus
• Alignment Length: 760
• Identity: 162/760 - (21%)
• Similarity: 225/760 - (29%)
• Gaps: 287/760 - (37%)

  Fly   165 ASVCGSDTTKENVCELCNKVFRYVTNLYRHKQRDHGILGKNGEDYEEDYYKCDLCDKTYKYVMAL 229
            |:|||.          |.|.||.:::|.:| ||.|     .|    |..|||.:|.|.:....|.
  Rat    82 AAVCGE----------CGKSFRQMSDLVKH-QRTH-----TG----EKPYKCGVCGKGFGDSSAR 126

  Fly   230 VKHKHKEHGSSLLSNNSGRKMPSTLAEDANPYSPASISETSTNQSRTNNDSLVHSIIKAVVLSDE 294
            :||:....|     ....|..|........|.|.....|..|
  Rat   127 IKHQRTHTG-----EKPYRVRPPAPGPPKMPRSRIPAGERPT----------------------- 163

  Fly   295 DGHSGEDSYYNCDQCSKSYKYIVSLIKHKHKEHLDKESYKQSDDEDDRPLASTSASASAPTAKPS 359
                      .|.:|.||::....|:||: :.|
  Rat   164 ----------ICGECGKSFRQSSDLVKHQ-RTH-------------------------------- 185

  Fly   360 RINRRVDGFDFHRSEPNGAKEIKCMICLRRF----TKLRELRNHLQNHPTDFDFEAHGEPIERIA 420
                            .|.|..||.||.:.|    .:::..|.|            .|:.:.|
  Rat   186 ----------------TGEKPYKCGICGKGFGDSSARIKHQRTH------------RGDQLPR-- 220

  Fly   421 EGFFKTAVESTAEGLKRRIFRDLRMGVYGRYYSITNQARYEMTLDSSDTDSDGDGDDNVVIRRSY 485
                                                                     .||.||..
  Rat   221 ---------------------------------------------------------PVVPRRQP 228

  Fly   486 SCELCDSPEARWPRKYLLHQHHQKEHTWLDAPHVCQRCDSRF-LNLQLLKHHTSQLCQNTLKRFM 549
            |..   :|||         .|..|..   |.|::|..|..|| |:..||.|..|.|..   |.|.
  Rat   229 SQA---APEA---------THRPKAQ---DKPYICTDCGKRFVLSCSLLSHQRSHLGP---KPFG 275

  Fly   550 CDKCPQRFFWRRNLRAHLVEHKCKQESYPCDQCSRSFQDKSAVTKHKLMMHRDSNMELLPCRWCT 614
            ||.|.:.|....:|..||..| ..::.|.|.:|.:.|.|.||..|| |..|  |......|..|.
  Rat   276 CDVCGKEFARGSDLVKHLRVH-TGEKPYLCPECGKGFADSSARVKH-LRTH--SGQRPHACPECN 336

  Fly   615 RTFYRPALLYKHLQRH----GFTGQDLPLAETLLADASKPAG------PKSVQCKICDIQFVSVA 669
            |:|...:.|.:|...|    .|:....|:|..:.:....|.|      |:| ..:..|..|
  Rat   337 RSFSLSSTLLRHRLTHMEPQDFSFSAYPVAPLIPSPPPPPLGTSPSLTPRS-PSQSSDGPF---- 396

  Fly   670 DLRRHISMQGHSDQPSAYMISTATGFELLLDDTDDSDEETSG-RTYSCDLCDLNFRRRREISEHQ 733
                  .:.|...:|..             ....:.....:| :.:.|..|...|||..::.:|
  Rat   397 ------GLPGLEPEPGG-------------PQAGEPPPPLAGDKPHKCPECGKGFRRSSDLVKH- 441

  Fly   734 YSLHSFDKLPHNCEHCIFKTVDKNMLHQHLRTQCMNTEKKFACMRCGYKFMWEENLAQHLSTQHS 798
            :.:|:                               .||.:.|..||..|.......:||.| |.
  Rat   442 HRVHT-------------------------------GEKPYLCPECGKGFADSSARVKHLRT-HQ 474

  Fly   799 KQPAVPEQQPPLRRKRRFRYQCPHCWRSFVV-QPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLT 862
            .:...|...|.|.|........|...:|.|. |||             .|.:.::|..||.|...
  Rat   475 GERTRPPPPPTLLRPHNPPGSVPIVPQSRVQGQPS-------------GPSQLHVCGFCGKEFPR 526

  Fly   863 PNKLNIHMRRHTGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPY 907
            .:.|..|.|.||||||:||..|...|........|:|.|...||:
  Rat   527 SSDLVKHRRTHTGEKPYKCAECGKGFGDSSARIKHQRGHLALRPF 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10669	NP_651388.1	zf-AD	4..80	CDD:462262
		C2H2 Zn finger	178..199	CDD:275368	8/20 (40%)
		C2H2 Zn finger	216..233	CDD:275368	5/16 (31%)
		C2H2 Zn finger	520..542	CDD:275368	10/22 (45%)
		C2H2 Zn finger	550..570	CDD:275368	7/19 (37%)
		C2H2 Zn finger	579..600	CDD:275368	9/20 (45%)
		C2H2 Zn finger	610..630	CDD:275368	6/19 (32%)
		C2H2 Zn finger	716..737	CDD:275368	6/20 (30%)
		C2H2 Zn finger	746..766	CDD:275368	0/19 (0%)
		C2H2 Zn finger	776..795	CDD:275368	6/18 (33%)
		C2H2 Zn finger	820..838	CDD:275368	6/18 (33%)
		C2H2 Zn finger	853..873	CDD:275368	7/19 (37%)
		zf-H2C2_2	866..889	CDD:463886	12/22 (55%)
		C2H2 Zn finger	881..901	CDD:275368	5/19 (26%)
		zf-H2C2_2	893..918	CDD:463886	5/15 (33%)
		C2H2 Zn finger	909..929	CDD:275368
Znf48	NP_001388702.1	zf-C2H2	84..105	CDD:395048	11/31 (35%)
		C2H2 Zn finger	85..105	CDD:275368	10/30 (33%)
		zf-H2C2_2	97..120	CDD:463886	12/32 (38%)
		C2H2 Zn finger	113..133	CDD:275368	6/19 (32%)
		COG5048	161..571	CDD:227381	132/654 (20%)
		C2H2 Zn finger	165..185	CDD:275368	7/20 (35%)
		C2H2 Zn finger	193..213	CDD:275368	5/19 (26%)
		C2H2 Zn finger	248..268	CDD:275368	8/19 (42%)
		C2H2 Zn finger	276..296	CDD:275368	7/19 (37%)
		C2H2 Zn finger	304..324	CDD:275368	9/20 (45%)
		C2H2 Zn finger	332..352	CDD:275368	6/19 (32%)
		C2H2 Zn finger	425..445	CDD:275368	6/20 (30%)
		C2H2 Zn finger	453..537	CDD:275368	26/97 (27%)
		C2H2 Zn finger	545..565	CDD:275368	5/19 (26%)