DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CHKov2 and CG14314

DIOPT Version :9

Sequence 1:	NP_651387.1	Gene:	CHKov2 / 43068	FlyBaseID:	FBgn0039328	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_650690.1	Gene:	CG14314 / 42179	FlyBaseID:	FBgn0038581	Length:	438	Species:	Drosophila melanogaster

Alignment Length:	376	Identity:	93/376 - (24%)
Similarity:	168/376 - (44%)	Gaps:	40/376 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 QWVTKELFSSLLEQSNRNFKAIIKFVPTSAISKGENYLTIVLRIQIEMQLKDNSIEDVSYILKIP 72
            |.::.|:|..:.:....:.: |..|.......:|:||...:.||::..:.:....|. :.|.|:
  Fly    24 QILSLEVFQDIFKHVEPDVQ-IDAFELAQGSDRGDNYTAALYRIKLTGKRRSLKWEQ-NVICKV- 85

  Fly    73 LVPED------EKNDFHEMFDAELDMYDHLIPELEDLYAKNTS-ISPKFKPVHLKFPGEPVKSDY 130
             :||.      .|:|  ::|..|:..|:.::|||....|..|: .:|.|..:...:   ..:.|.
  Fly    86 -MPESVVAREAYKSD--KLFRNEVQFYNTIMPELLKFQASKTNQDTPVFNAIPKCY---SARHDL 144

  Fly   131 ILLEDLRKKGYRNADRTQGLEQFEVEAVLKKLAQWHAASA----KRVVELGEYEKDIRESYFTT- 190
            :::||||::|::.:||.:||...|.::||.::||.|..|.    ::.:|.......|.|..|.|
  Fly   145 LIMEDLRERGFQMSDRHKGLSLEETQSVLLQVAQLHGLSLAYKFEKPLEFSNLCSMISEGIFCTA 209

  Fly   191 ------EHQKLLDEFNINFCMPFLECMQQYNLEPGQLVLISDYTSQLTDLNIEFGKNDPLELSVL 249
                  .:.:.|.:..|......|....:|.|...:....|.:..::..|     .:....||.:
  Fly   210 NTSWYRNYYERLTKNAIQMVSEVLPPDSKYVLAMNKFAESSSFFGRMVKL-----ASTESPLSAI 269

  Fly   250 NHGDFWCNNFMFKY--KNASEVEDVCFVDFQLPKYGTPAQDLLCILMTSPKFSIKLDKFDYFIEY 312
            .|||.|.|||::.|  ::...|.:|..:||||.:|.:.|.|:..:|.......::..:....::.
  Fly   270 CHGDCWVNNFLYHYDPEDPHRVLEVALLDFQLIRYSSIALDIANLLYCCTTKEMRDAQLQTLLKI 334

  Fly   313 YHQQLVEHLTML--NYNRNAPTLSK----FHAHLHRYSLWAFICAQRMLPI 357
            |.::|...|.||  |...:..||.|    |...|..|..:|...|..:|||
  Fly   335 YTEELFRWLQMLCTNLPDHCDTLQKLQDLFAEELKTYGRFALGLALDILPI 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CHKov2	NP_651387.1	EcKinase	40..326	CDD:281023	76/307 (25%)
CG14314	NP_650690.1	EcKinase	56..346	CDD:281023	74/302 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I4070
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.060