DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CHKov1 and CG6830

DIOPT Version :9

Sequence 1:	NP_001097918.1	Gene:	CHKov1 / 43067	FlyBaseID:	FBgn0045761	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster

Alignment Length:	413	Identity:	171/413 - (41%)
Similarity:	261/413 - (63%)	Gaps:	13/413 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IPDWVTAERFEDVLKSNVDGYSKVRNFKAEMGSAAGDNYATNMLRVNIEVELQDGTTKELSYMVK 70
            :|.|:...:||::|.::||.:||:..|:.:...|.|:||||.|||::|:|||.|.:||.:|:|:|
  Fly    46 VPKWLNQTQFEELLAADVDQFSKIVGFRVKPAMAPGENYATLMLRISIDVELTDKSTKLVSFMMK 110

  Fly    71 LPRQREINKEMMKHNNIFEIERTMYNLVVPEMEALYKAAGVEVTFGAKSYEL------KNAQTEY 129
            :|......::||...|.|..|...|..::|:||.||||.|:::.|..::::|      |.|.|
  Fly   111 VPHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRAFKLDATKEPKVANT-- 173

  Fly   130 ISLEDLCIKGFKNANRLEGLDQAHTERVLRKLAQWHAATAVRVATKGQYPEIVLNGFF---KEEN 191
            :.:.||...||||.||||.|:...|:..|.:|||:|||.|..|...|.||:|.:||..   ||..
  Fly   174 VLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPYPDIFVNGVMGNNKEAI 238

  Fly   192 RPMMNDMMNGMGQVFVKCCSTYEGNEAYIEKV-KALKDVMIDELFKMCVVDPTEFNVLNHGDSWS 255
            ...|..|:......|:.....::..|.|.||: |||..:.: |..|:.:|||.|||.|||||.|.
  Fly   239 IAFMEGMLASFRTSFMANLDKFKNGEEYREKLEKALAGLTM-EFMKLGIVDPNEFNALNHGDCWM 302

  Fly   256 NNIMFQYDESGKIKEVYMVDFQVSKYGTVAQDLYYFLISSTKLEDKLSKFDYYVKVYHDNLVEHL 320
            ||::|:.:.||.::::..||||..|||:.|.||.||:|||.:::.|||.||::::.|.:.||:||
  Fly   303 NNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSVQIDYKLSHFDFFIRHYQEALVKHL 367

  Fly   321 KILKYSKPLPSLRDIHKSLYKYGTFAYSVATGVMAAVLVDPTESASFENFVGDSAEGADFQMKMY 385
            .||.::...||||::|::|.|||.:.......|:..||:|||:||:|:||:.|||:|..|:..:|
  Fly   368 GILGFTGRKPSLRELHRTLIKYGGWVLFPTISVLPLVLLDPTQSATFDNFMSDSADGVSFRGSLY 432

  Fly   386 NNPRYRKHMQAILPWLLNRGALD 408
            .|.|.:::::.|||||.|||.|:
  Fly   433 ANKRCQEYIERILPWLDNRGFLE 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CHKov1	NP_001097918.1	EcKinase	41..325	CDD:397213	123/293 (42%)
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	123/294 (42%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442531
Domainoid	1	1.000	57	1.000	Domainoid score	I17979
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850