DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10562 and CG6834

DIOPT Version :9

Sequence 1:	NP_651385.3	Gene:	CG10562 / 43066	FlyBaseID:	FBgn0039326	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster

Alignment Length:	412	Identity:	168/412 - (40%)
Similarity:	262/412 - (63%)	Gaps:	17/412 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PDWVTAEIFEDLLKANVDGYSKIKNFKADIGSAAGENYATIMLRVKIEVELQDGKSKSVSYMVKL 71
            |:|:....||:||.|:||.:|||..|:.....|.||||||:|||:.|:|||.|..:|.|.:|:|:
  Fly    62 PEWLNQTQFEELLAAHVDQFSKIVGFQVKPAMAPGENYATLMLRISIDVELTDKSTKLVCFMLKV 126

  Fly    72 PHQVEAIQEMMKRTNIFEIERTMYNEVVPELEALYKAVGVDITFGAKNYDLKNAK----TDYVAL 132
            ||.|..:::|:...|.|..|..:|::::|:||.||||.|:||||..|.:.|.:.|    .:.|.:
  Fly   127 PHNVPQMEQMLAMANFFNSENKVYSDILPKLEELYKAKGLDITFAPKAFKLDSVKEPKLANTVLM 191

  Fly   133 EDLGLKGFKNANRLEGLDQEHTERVLRKLSQWHAASAVRVATKGPYPKILLQGFFKEESRPVMSE 197
            .||...||||.||||.|:.|.|:..|:||:|:||||::.|...|||....:.|.. ..::.|:..
  Fly   192 SDLSQDGFKNLNRLECLNLEQTKFALKKLAQFHAASSMNVQVNGPYEDQFVNGVM-GGNKEVLMA 255

  Fly   198 MIKGMGANF----VKSCATYEGHEAYLDKV-KALQPVAIDKIFE-FAKVEPTEFNVLNHGDSWSN 256
            ..:||.|:|    :.:...::..|.:.:|: ||...:.:|  || ....:|.|||||||||.|.|
  Fly   256 FYEGMVASFRTALMANLKNFKNGEEFREKLEKAFVQIFLD--FEHLMTADPDEFNVLNHGDCWMN 318

  Fly   257 NIMFQYDAFGKIKEVYLVDYQLPKYGTVAQDLLYFLLSSTKLEDKLAKFDYYIKIYHDNLVEHLK 321
            |::|:.|:.|:::::..||:|.||||:..|||.|.:|:|..::.||..|:|:|:.||:.|.:||.
  Fly   319 NLLFKLDSKGEVQDMLFVDFQNPKYGSPTQDLFYLILTSVHIDYKLDYFEYFIRHYHEQLTQHLD 383

  Fly   322 ILKYSKPIPSLRDIHLALFKYGYFGYTVATGVMSAVLLDPTDSASLENFIGGSD----FQMQLYN 382
            :|.::...||||::|:.::|:|.:....:.||:..|||||.:||:.|||:|.|:    |:..||.
  Fly   384 LLGFTGKQPSLRELHMLMYKHGSWAVFPSIGVLPIVLLDPNESATFENFLGDSESSAKFKNLLYT 448

  Fly   383 SPRYRKHIQAVMPWLLNRGALE 404
            :.||..:|:.::|||.|:|.||
  Fly   449 NKRYHGYIEKLLPWLDNKGFLE 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10562	NP_651385.3	EcKinase	41..325	CDD:281023	120/293 (41%)
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	120/294 (41%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442548
Domainoid	1	1.000	57	1.000	Domainoid score	I17979
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850