DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10562 and CG11891

DIOPT Version :9

Sequence 1:	NP_651385.3	Gene:	CG10562 / 43066	FlyBaseID:	FBgn0039326	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_001027211.3	Gene:	CG11891 / 3772439	FlyBaseID:	FBgn0039309	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	422	Identity:	103/422 - (24%)
Similarity:	200/422 - (47%)	Gaps:	39/422 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IPDWVTAEIFEDLLKANVDGYS-KIKNFKADIGSAAGENYATIMLRVKIEVELQDGKSKSVSYMV 69
            :|.|:|.:..|..|::.....| ::.|....:....||||::::.|:.:|......|.|..:...
  Fly    12 VPAWLTRDYVEQKLRSYFRNDSLRLVNLDIKLALGNGENYSSVITRIYVEYTTDKSKDKQSTRFT 76

  Fly    70 KLPHQVEAIQEMMKRTNIFEIERTMYNEVVPELEALYKAVGVDI--TFGAKNYDLKNAKTDYVAL 132
            :......|.|.::. ..::..|..:|..::|::..:.:....|.  .|....|  .:.|.|.:..
  Fly    77 RFADAGPAAQVLLS-YGVYNRELDLYERILPQMAEVVRNELADSRKLFAGTVY--VDRKRDSIIF 138

  Fly   133 EDLGLKGFKNANRLEGLDQEHTERVLRKLSQWHAASAVRVATKGP--YPKILLQGFFKEESR--- 192
            ||:.|:.::.|:||:.||.|||..||.||:.:|||.|. :|.:.|  :.|...:|||.:.:|
  Fly   139 EDMSLENYRVADRLKKLDLEHTHLVLEKLANFHAAGAA-LAERQPGIFAKNFDRGFFNQHTRGYE 202

  Fly   193 PVMSEMIKGMGANFVKSCATYEGHEAYLDKVKALQPVAIDKIFEFAK----VEPTEFNVLNHGDS 253
            |:|..::..:..:........:.::|.:|::       ::.:.|:.:    :.|.:|..|.|||.
  Fly   203 PIMKNLLMALSRSLELEPDLCQRYQAKIDRL-------VENVMEYGERSTTIVPGDFLTLAHGDL 260

  Fly   254 WSNNIMFQYDAFGKIKEVYLVDYQLPKYGTVAQDLLYFLLSSTKLEDKLAKFDYYIKIYHDNLVE 318
            |:.|||||||..|.......:|:|...:.:.|.||.||..::.:.:.:|.|....::.|:..|..
  Fly   261 WTTNIMFQYDDKGHPINAIFIDFQFSAWNSPAIDLHYFFSTALQADIRLKKQPELVQFYYYKLNA 325

  Fly   319 HLKILKYSKPIPSLRDIHLALFKYGYFGYTVATGVMSAVLLDPT------DSASLENFIG----G 373
            .||.::||..:|||...|.......::      ...::::.:||      :.||::..|.    |
  Fly   326 ALKKVQYSGNVPSLFVFHQQFRNRSFY------AAFASLIFEPTMTYTGKEEASMDQIISLSEKG 384

  Fly   374 SDFQMQLYNSPRYRKHIQAVMPWLLNRGALEL 405
            ..|:...:.:...||.::..:|:|.:.|.|::
  Fly   385 MRFKDDAFQAEETRKKMRLTLPFLDHLGLLDV 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10562	NP_651385.3	EcKinase	41..325	CDD:281023	77/294 (26%)
CG11891	NP_001027211.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	4	4.010