DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10562 and CG9497

DIOPT Version :9

Sequence 1:	NP_651385.3	Gene:	CG10562 / 43066	FlyBaseID:	FBgn0039326	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_001260130.1	Gene:	CG9497 / 33884	FlyBaseID:	FBgn0031800	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	426	Identity:	119/426 - (27%)
Similarity:	206/426 - (48%)	Gaps:	50/426 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PDWVTAEIFEDLLK-----ANVDGYSKIKNFKADIGSAAGENYATIMLRVKIEVELQDGKSKSVS 66
            |..:....||::|:     |.|    ::.:....:||:.||||.:.:.|||:..:..|...:.::
  Fly    14 PSHLDVPFFEEVLETALRTARV----QLLSIHIRMGSSTGENYCSQIYRVKVSFKRPDHPEQHMA 74

  Fly    67 YMVK-LPH--QVEAIQEMMKRTNIFEIERTMYNEVVPELEALYKAVGVDITFGAKNYDLKNAKTD 128
            ::|| :||  .||.|.::    .::..|:..|.||:|.||.|.:.   :..||.|.|.......:
  Fly    75 FIVKSIPHLDSVEFIDDL----QVYLKEKITYYEVLPRLELLMQC---NRRFGPKLYHYLKQPEN 132

  Fly   129 YVALEDLGLKGFKNANRLEGLDQEHTERVLRKLSQWHAASAVRVATKGP-----YPKILL--QGF 186
            .:..|||..|||..|:|..||::||.:.|:.:|:::||.| :.:|...|     |...:|  :|.
  Fly   133 SLVFEDLAEKGFVMASRELGLNEEHCQLVMERLAEFHATS-MALAVVDPHIFDAYGDGMLSPRGL 196

  Fly   187 FKEESRPVMSEMIKGMGANFVKSCATYEGHEAYLDKV-KALQPVAIDKIFEFAKVEPT------E 244
            .|::.  ::.:...|.|.......:|:.|.|...:|: |.:|.       :.|.:|.:      |
  Fly   197 AKDDG--LLMQFFSGNGKELHHLVSTWPGFEKIAEKIGKYMQN-------QRANLERSQAPQEKE 252

  Fly   245 FNVLNHGDSWSNNIMFQYDAFGKIKEVYLVDYQLPKYGTVAQDLLYFLLSSTKLEDKLAKFDYYI 309
            ..||||||.|.||::|:||...:.:::.|:|:||..:|:...||.||..:|..||....:....:
  Fly   253 VKVLNHGDLWVNNMLFKYDGAQRPQDLILIDFQLSVWGSPGIDLNYFFYTSLTLEVLRHRRTQLL 317

  Fly   310 KIYHDNLVEHLKILKYSKPIPSLRDIHLALFKYGYFGYTVATGVMSAVLLDPTDSA--SLENFIG 372
            :.||..|.:.|..|....|:||...|...:.:...:|:..:.|:...|..|...:|  :|||| .
  Fly   318 RTYHARLAKTLLDLDMGIPVPSYEQILEEVHRRESYGFFASYGIFPTVSQDKAQTADNNLENF-K 381

  Fly   373 GSDFQ----MQLYNSPRYRKHIQAVMPWLLNRGALE 404
            .:||.    .|::.|.|....::..:|.....|.|:
  Fly   382 DADFAKQKVRQMFQSRRLADTLRYTLPHFERAGVLD 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10562	NP_651385.3	EcKinase	41..325	CDD:281023	90/300 (30%)
CG9497	NP_001260130.1	EcKinase	49..331	CDD:281023	89/298 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459266
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	8	7.860