DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10562 and CG33510

DIOPT Version :9

Sequence 1:	NP_651385.3	Gene:	CG10562 / 43066	FlyBaseID:	FBgn0039326	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_001014493.2	Gene:	CG33510 / 3346224	FlyBaseID:	FBgn0053510	Length:	426	Species:	Drosophila melanogaster

Alignment Length:	362	Identity:	81/362 - (22%)
Similarity:	150/362 - (41%)	Gaps:	41/362 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 EVELQDGKSKSVS--YMVKLPHQVEAIQEMMKRTNIFEIERTMYNEVVPELEALYKAVGVDITFG 116
            :.:|:|.|....|  ::..:..|...::..|::..:.|.|..:| :::.||:...|.|     :.
  Fly    65 QYQLEDQKDVQTSRLFVKSVIFQNANMEFYMEKMGLIEKEIKLY-DLLNELKKFSKHV-----WS 123

  Fly   117 AKNYDLKNAKTDYVALEDLGLKGFKNANRLEGLDQEHTERVLRKLSQWHAASAVRVATKGPYPKI 181
            ||.|..:........:||:|........|.  |::.....:|:.|:..||:|......:|....:
  Fly   124 AKCYFTRKDLFVMQNVEDMGYVALPPGTRF--LNENQMGPILKSLATLHASSIAYEKQQGKTIGV 186

  Fly   182 LLQGFFKEES-RPVMSEMIKGMGANFVKSCATYEGHEAYLDKVKALQ------PVAIDKIFEFAK 239
            ..:.:.||.| .|.:.....|:.|  |.:.|..  |...||..:|.:      |..:||::....
  Fly   187 EFRKWLKEVSVDPEVEWYTTGLRA--VLAVAAI--HPDVLDNPEAQEYIAQELPRCLDKVYCMVN 247

  Fly   240 VEPTEFNVLNHGDSWSNNIMFQYDAFGKIKEVYLVDYQLPKYGTVAQDLLYFLLSSTKLE--DKL 302
            ..|...||..|.|:|:.|:.:..:...:.:.: |||:||.:|...|.|  :.|::...||  .:.
  Fly   248 PSPVHRNVFVHRDAWNANVFYHKEKPHEERSI-LVDFQLCRYSPPAMD--FHLVTYLNLEPFSRK 309

  Fly   303 AKFDYYIKIYHDNLVEHLK---ILKYSKPIPSLRDIHLALFKYGYFGYT---VATGVMSAV---- 357
            ......|:.|:|.|.|..:   :..|.:.: |.::...:|..:..||.|   :|..|:...
  Fly   310 KMIGSLIETYYDALAEEFREMGVNPYQEQL-SKQEFEQSLNDFSLFGATYNCIAATVLRLPDNYL 373

  Fly   358 --LLD--PTDSASLENFIGGSDFQMQLYNSPRYRKHI 390
              |.|  |.|.....|....:|....:.|.|.:..::
  Fly   374 KNLKDERPEDFHRFCNVDRSADVLRLMKNHPEFADYM 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10562	NP_651385.3	EcKinase	41..325	CDD:281023	65/284 (23%)
CG33510	NP_001014493.2	CHK	134..329	CDD:214734	49/203 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459699
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	5	4.840