DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10562 and CG31288

DIOPT Version :9

Sequence 1:	NP_651385.3	Gene:	CG10562 / 43066	FlyBaseID:	FBgn0039326	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_733094.1	Gene:	CG31288 / 318664	FlyBaseID:	FBgn0051288	Length:	428	Species:	Drosophila melanogaster

Alignment Length:	417	Identity:	137/417 - (32%)
Similarity:	227/417 - (54%)	Gaps:	30/417 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IPDWVTAEIFEDLLKANVDGYSKIKNFKADIGSAAGENYATIMLRVKIEVELQDGKSKSVSYMVK 70
            ||||:..:.||.:|..:...:.|:..|........|||:.:.||||.|::|::||..|:.:|:.|
  Fly    16 IPDWINEKYFESVLAKDEPDHVKVLKFTVVAAIPPGENFTSTMLRVYIKLEMKDGSVKTKTYIFK 80

  Fly    71 LPHQVEAIQEMMKRTNIFEIERTMYNEVVPELEALYKAVGVDITFGAKNYDLKNAKTD-YVALED 134
            .....|.....:....:|..|..||...:|..|||||.||.||....|....:..:.| :...||
  Fly    81 TMLPEERGGSDINEFGLFPKEAMMYKTYLPAFEALYKDVGWDIQLAPKCLHTEEREGDIHFIFED 145

  Fly   135 LGLKGFKNANRLEGLDQEHTERVLRKLSQWHAASAVRVATKGPYPKILLQGFFKEESRPVMSEMI 199
            |.:|.|||.:|.:|||.||..:.|:||:::||||||.....||||....:||.|::.:....:..
  Fly   146 LCVKRFKNMDRTKGLDMEHMTKCLQKLAEYHAASAVYEELHGPYPSEFSEGFVKKDVKKFHVDGF 210

  Fly   200 KGMGANFVKSCATYEGHEAYLDK-VKALQPVA--IDKIFEFAKVEPTEFNVLNHGDSWSNNIMFQ 261
            :.....:.|:..::...:|  || :||...|.  ..:.....::.|.||:||||||.||:|:|..
  Fly   211 QLKEKAYKKAMLSWGLKDA--DKYIKAFPTVKQYWAQCLSTLELNPDEFHVLNHGDFWSSNLMSS 273

  Fly   262 YDAFGKIKEVYLVDYQLPKYGTVAQDLLYFLLSSTKLEDKLAKFDYYIKIYHDNLVEHLKILKYS 326
            |...|.::::.|:|:|:..:|:.|.|||:||..|...:.::.:||::::||.:.|||.||:||..
  Fly   274 YLPDGTLEKLILIDFQIVMWGSPAMDLLFFLTLSPTNDLRIKEFDHFVRIYWERLVECLKVLKLK 338

  Fly   327 KPIPSLRDIHLALFK-----YGYFGYTVATGVMS--AVLLDPTD--------SASLENFIGGSDF 376
            ||:|.|||:..::..     |.:|      .:::  .::|.|||        ||:.|.   |.::
  Fly   339 KPLPKLRDLQNSMNNKNHSFYAFF------SILNHLPIILFPTDKDSNIHNLSANTEE---GENY 394

  Fly   377 QMQLYNSPRYRKHIQAVMPWLLNRGAL 403
            :::|.::|.:...::.:.|:|.|||.|
  Fly   395 RLRLLSNPAFGNVMKDLYPFLYNRGIL 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10562	NP_651385.3	EcKinase	41..325	CDD:281023	103/287 (36%)
CG31288	NP_733094.1	EcKinase	50..331	CDD:281023	99/282 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442499
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I6344
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	9	8.910