DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10560 and CG6830

DIOPT Version :9

Sequence 1:	NP_651384.2	Gene:	CG10560 / 43065	FlyBaseID:	FBgn0039325	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster

Alignment Length:	427	Identity:	158/427 - (37%)
Similarity:	246/427 - (57%)	Gaps:	17/427 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PPQTNDENVCEREVPIPGWVKPEVFEDLLKDNVKDYKKTKALRAKAGVAAGENYATIMLRLELDV 66
            ||...:..|...:: :|.|:....||:||..:|..:.|....|.|..:|.||||||:|||:.:||
  Fly    32 PPNKPEPEVDHSDL-VPKWLNQTQFEELLAADVDQFSKIVGFRVKPAMAPGENYATLMLRISIDV 95

  Fly    67 ETKDKSEVTKAFMLKTPHDTDAYRKLLQETNIFDVERGMYLVVVPELEQMYRDVGLEVKFGAEAY 131
            |..|||....:||:|.||||....:::...|.|..|...|..::|::|::|:..||::||...|:
  Fly    96 ELTDKSTKLVSFMMKVPHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRAF 160

  Fly   132 EIKVSE-----NYVLLEDLRPRGFKNVDRLQGLDQAHTESVLRKFAQWHAASAVRVDLKGPYEEK 191
            ::..::     |.||:.||...||||::||:.|:...|:..|.:.||:|||.|..|.:.|||.:.
  Fly   161 KLDATKEPKVANTVLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPYPDI 225

  Fly   192 YTNGFF-KSKEIMNFFCD------RSAKILLNNIDQYDGHAAYIKDLQSVSEKLFDIYNDIKEPK 249
            :.||.. .:||.:..|.:      |::  .:.|:|::.....|.:.|:.....|...:..:....
  Fly   226 FVNGVMGNNKEAIIAFMEGMLASFRTS--FMANLDKFKNGEEYREKLEKALAGLTMEFMKLGIVD 288

  Fly   250 SDEFNALNHGDGWSNNIMFQYNDKNEISNTYFVDLQLPKWGSVAQDLYYFLLSSTSLDIKTEKFD 314
            .:|||||||||.|.||::|:.|...::.:..|||.|.||:||.|.||.||::||..:|.|...||
  Fly   289 PNEFNALNHGDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSVQIDYKLSHFD 353

  Fly   315 YFVWFYHSELVKHLKLLNYSKKLPTLRSIRNALNKYSGWAFICSISVMGVVLLDPTDDADFDKII 379
            :|:..|...|||||.:|.::.:.|:||.:...|.||.||....:|||:.:||||||..|.||..:
  Fly   354 FFIRHYQEALVKHLGILGFTGRKPSLRELHRTLIKYGGWVLFPTISVLPLVLLDPTQSATFDNFM 418

  Fly   380 SN--EHSNFTNSIYTNPRYRRHMKVVLPWLQHRGALE 414
            |:  :..:|..|:|.|.|.:.:::.:||||.:||.||
  Fly   419 SDSADGVSFRGSLYANKRCQEYIERILPWLDNRGFLE 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10560	NP_651384.2	EcKinase	52..333	CDD:281023	110/292 (38%)
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	110/293 (38%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442525
Domainoid	1	1.000	57	1.000	Domainoid score	I17979
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101022at50557
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850