Protein Alignment CG10553 and nhr-246

DIOPT Version :10

• Sequence 1: NP_651383.1
• Gene: CG10553 / 43064
• FlyBaseID: FBgn0039324
• Length: 414
• Species: Drosophila melanogaster
• Sequence 2: NP_001256661.1
• Gene: nhr-246 / 191499
• WormBaseID: WBGene00014192
• Length: 386
• Species: Caenorhabditis elegans
• Alignment Length: 382
• Identity: 85/382 - (22%)
• Similarity: 148/382 - (38%)
• Gaps: 95/382 - (24%)

  Fly    27 EELLKRIVKDYKATKSMRANAGVAAGEN----YATVMLRIELDVEKEDNTQTTKAFMLKTPHQSE 87
            :|.|..:::.....|......|:.  ||    :.:::.::.|..   ||....|..:||.|..::
 Worm    13 KEWLAELIEIKIGVKPKIGTVGIL--ENSELGFMSLLRKVRLHF---DNDDLPKHVVLKIPQNTK 72

  Fly    88 QYRKV------IEKTDIFDVERGM------YVEVVPELEQLYRDVGLEVKFGAELYDIEASDYYV 140
            ....|      ::..|...|||.|      |.::...|.:  :.:.:...:.|.....:|....:
 Worm    73 GCSVVENAGGGVKNVDHSVVERFMHNTECNYYKLFSSLSE--KPLQIPTTYLASKAGEKAPVPVI 135

  Fly   141 LLE--------DLRPRGFGNIDRLEGMDQAHTECVLKKFAQWHAASAVRVETKG--PYQEKYT-K 194
            :||        ||.| || |.|:|..        ::.:..:.|..|....:.|.  |.:.|.. .
 Worm   136 VLEMLEDCKLHDLIP-GF-NEDQLFK--------IVDELVKLHIFSLTTEKWKEIVPDESKLAMS 190

  Fly   195 GFL------------RNEE--IVDAFINRSIKVFLDNVHLCKGYETYLNDLRIVSGKTFEIVESL 245
            |||            :|.|  ::.:::..::..  |..:|.|..:.|:|:.|
 Worm   191 GFLQCMVADVGRKLAQNPELGVILSYVENTLDT--DPNYLQKMRDEYINEER------------- 240

  Fly   246 NNPSPDEFIALNHGDGWANNIM--SQYNTKGEIQDTYFVDLQVPKWGSVTQDLYYFLLSSTSLDI 308
              ||     .:.|||.||..|:  .:.|..|      .||.|....||..:||::.|.:.||:..
 Worm   241 --PS-----VICHGDLWAPQILWDKEDNIAG------IVDWQATHRGSPMEDLHHILSTCTSVQN 292

  Fly   309 KTSKFDYFIWFYHSELVKHLKLLGYSKTLPTLRRINDALNKYSGWSFI--CTATILA 363
            :.:.....:..|:::|...||..|: ||..|...|:...|    :|||  .:.||.|
 Worm   293 RKTFTKPLLDHYYNKLKVGLKEKGF-KTTWTREEIDIEYN----YSFIYGASRTIFA 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10553	NP_651383.1	EcKL	52..333	CDD:397213	69/323 (21%)
nhr-246	NP_001256661.1	CHK	134..314	CDD:214734	49/217 (23%)