DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10559 and CG10562

DIOPT Version :9

Sequence 1:	NP_651382.2	Gene:	CG10559 / 43063	FlyBaseID:	FBgn0039323	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_651385.3	Gene:	CG10562 / 43066	FlyBaseID:	FBgn0039326	Length:	405	Species:	Drosophila melanogaster

Alignment Length:	409	Identity:	187/409 - (45%)
Similarity:	277/409 - (67%)	Gaps:	8/409 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 TAPMPTWLRANLFEELLSKRYGGNYAGIKSFKPEAGLKPGENYSTIMLRLKLEVELQDHTIENVS 71
            ::.:|.|:.|.:||:||.....| |:.||:||.:.|...||||:|||||:|:||||||...::||
  Fly     3 SSKIPDWVTAEIFEDLLKANVDG-YSKIKNFKADIGSAAGENYATIMLRVKIEVELQDGKSKSVS 66

  Fly    72 YMLKTPYDFEMYREILRKNNMFAVERDVFIQVIPELEQMYKDVGVEVKFGAKAYEI-DAPDDYVL 135
            ||:|.|:..|..:|::::.|:|.:||.::.:|:||||.:||.|||::.||||.|:: :|..|||.
  Fly    67 YMVKLPHQVEAIQEMMKRTNIFEIERTMYNEVVPELEALYKAVGVDITFGAKNYDLKNAKTDYVA 131

  Fly   136 LQDLGPLGFRNVDRLEGLDMVHTKCVLKKMAQWHAVSATRIHLKGPYPQNYLQPTYADTMKESIE 200
            |:|||..||:|.:||||||..||:.||:|::||||.||.|:..|||||:..||..:.:..:..:.
  Fly   132 LEDLGLKGFKNANRLEGLDQEHTERVLRKLSQWHAASAVRVATKGPYPKILLQGFFKEESRPVMS 196

  Fly   201 QVAETLGKYFLKCLPLYEGYEEYSAAVHKMQPKIVDLMYAMNTPDPQDFNALNHGDCWTSNIMFK 265
            ::.:.:|..|:|....|||:|.|...|..:||..:|.::.....:|.:||.|||||.|::||||:
  Fly   197 EMIKGMGANFVKSCATYEGHEAYLDKVKALQPVAIDKIFEFAKVEPTEFNVLNHGDSWSNNIMFQ 261

  Fly   266 YEDESPEPIETYFVDLQLPKVTSVAYDLIYFLLGSTKFEIQLSQFDYFIKYYHDHLVEHLRMLNY 330
            | |...:..|.|.||.||||..:||.||:||||.|||.|.:|::|||:||.|||:|||||::|.|
  Fly   262 Y-DAFGKIKEVYLVDYQLPKYGTVAQDLLYFLLSSTKLEDKLAKFDYYIKIYHDNLVEHLKILKY 325

  Fly   331 PEAKTPTLGFLHTQLLKYGRVGYHIAFILCPPVLLDRTEDANLTDFVTETDNGDGLKLAMYSNAR 395
            .: ..|:|..:|..|.|||..||.:|..:...||||.|:.|:|.:|:    .|...::.:|::.|
  Fly   326 SK-PIPSLRDIHLALFKYGYFGYTVATGVMSAVLLDPTDSASLENFI----GGSDFQMQLYNSPR 385

  Fly   396 YKKHVSAILKWLNNRGAFQ 414
            |:||:.|::.||.||||.:
  Fly   386 YRKHIQAVMPWLLNRGALE 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10559	NP_651382.2	EcKinase	45..330	CDD:281023	141/285 (49%)
CG10562	NP_651385.3	EcKinase	41..325	CDD:281023	141/284 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442487
Domainoid	1	1.000	57	1.000	Domainoid score	I17979
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I6344
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	8	8.000