DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10559 and CG10513

DIOPT Version :9

Sequence 1:	NP_651382.2	Gene:	CG10559 / 43063	FlyBaseID:	FBgn0039323	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_651370.2	Gene:	CG10513 / 43051	FlyBaseID:	FBgn0039311	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	426	Identity:	110/426 - (25%)
Similarity:	193/426 - (45%)	Gaps:	46/426 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PMPTWLRANLFEELLSKRYGGNYAGIKSFKPEAGL-------KP----GENYSTIMLRLK-LEVE 61
            |.|.||.....|.||           :..|.:.||       ||    |:||:::|.|:: |.::
  Fly    14 PAPEWLDETYLERLL-----------RDLKNDPGLRITDLVIKPATAKGDNYASVMTRVRILFLK 67

  Fly    62 LQDHTIENVSYMLKTPYDFEMYRE-ILRKNNMFAVERDVFIQVIPELEQMYKDVGVEVKFGAKAY 125
            ....:.|...|::||.|:.:.:.. |..:..:...|..::.:::|:|..:.:......|..||..
  Fly    68 SGAKSPETEYYIVKTTYENDAFASGIFSQYQVSTTEMRMYEKILPQLSSLIEKTRQPEKVFAKTL 132

  Fly   126 EIDAPDDYVLLQDLGPLGFRNVDRLEGLDMVHTKCVLKKMAQWHAVSATRIHLKGPYPQNYLQPT 190
            .:|...:.::.:||....:...|||.|.|:.||:..|:|:|:.||.:|.         .|..||.
  Fly   133 HVDYEHEAIIFEDLAVTKYVLADRLVGFDLEHTRLGLRKLAKMHAAAAV---------LNERQPG 188

  Fly   191 YADTMKESI-EQVAETLGKYFLKCLPLYEGY--------EEYSAAVHKMQPKIVDLMYAMNTPDP 246
            ........| .:..:....:|:..:.:...:        |.|:..:.|:|.::::....:..|.|
  Fly   189 LLTKFDHGIFNRHTQAFAPFFVNTVGVAADFARECPELGERYATKLKKLQERVMEYSTRVYDPQP 253

  Fly   247 QDFNALNHGDCWTSNIMFKYEDESPEPIETYFVDLQLPKVTSVAYDLIYFLLGSTKFEIQLSQFD 311
            .|||.|.|||.|.:|:|.:| .|:.||::...:|.|....:|.|.||.||...|.:.:|:..|.|
  Fly   254 GDFNTLVHGDYWVNNVMLRY-GENKEPLDMTLIDFQFCSWSSPAVDLHYFFNTSVQVDIRYEQQD 317

  Fly   312 YFIKYYHDHLVEHLRMLNYPEAKTPTLGFLHTQLLKYGRVGYHIAFILCPPVLL-DRTEDANLTD 375
            ...:|||..|||.|:.||: ....|||.....| |:.||.......::|..:|. |:..||:...
  Fly   318 ALFQYYHTVLVETLKDLNF-GGYIPTLRQFVLQ-LERGRFFAVTVALVCQAILTNDQNADADFNA 380

  Fly   376 FVTETDNGDGLKLAMYSNARYKKHVSAILKWLNNRG 411
            .:.:.:.|...:..:|:|.|.:.::...|...:..|
  Fly   381 LMKDDERGRNFRKVLYTNKRLQDNLKRELPRFDRSG 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10559	NP_651382.2	EcKinase	45..330	CDD:281023	80/299 (27%)
CG10513	NP_651370.2	EcKinase	50..336	CDD:281023	79/295 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459462
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	6	5.950