DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31087 and CG6830

DIOPT Version :9

Sequence 1:	NP_001262952.1	Gene:	CG31087 / 43062	FlyBaseID:	FBgn0051087	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster

Alignment Length:	410	Identity:	151/410 - (36%)
Similarity:	249/410 - (60%)	Gaps:	9/410 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PAN--NLPSWLSKISLEKAVQAQIGDFEKIISVIPQKGSSDGDNYSTQFLRLLVEVELIDHSTKD 75
            |.|  .:|.||:....::.:.:...:||||:|...:..:..|||::::.|::.:|.:|.|:|.|.
  Fly   476 PENTDQIPDWLNIDDFKEIILSAEPNFEKILSSTSKLATKPGDNFASKLLKVEIEAQLKDNSVKT 540

  Fly    76 LSFVLKAQHSNEMMAAILAKLKLFQKEEQMYHSILPKFEKLYADAGKPIQFAPKAFKFDRDLGVD 140
            .|::||....|:  |...:...||.||.::|.:.:|.||:.|.|.|.|:.|:||:|:..:|:..:
  Fly   541 FSYILKVHSDND--AINFSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSFRLSKDVSKE 603

  Fly   141 YILLEDLHRKNFKNANRLAGLDLDHMHKVLEKLAAFHAASACYVEHHGLFGEEFTVGVFSESNRQ 205
            |:|||:|....||..:|:.|:||:|....|:|||.:||||..|.|.:|.:..::..|:|:|....
  Fly   604 YLLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPKYNNGIFTEQTAP 668

  Fly   206 LLQEF--NASGAFLAQLKKWKNAQKIYEKLADSDDYLVDRLLQDQQYNTREFNVLNHGDCWANNV 268
            :.:..  |...:|:.::.|:....:...|:.:..|..|||:|:|.:.|.:.||||||||.|.||:
  Fly   669 IFKGMFVNTKKSFIEEVSKFDGVDEYLHKMPEILDTYVDRILEDAKINEQAFNVLNHGDAWINNI 733

  Fly   269 MYQHDAFGTIKETLFVDFQVGKYGSPANDLYYLILSSAAPELKTAKFDYLVRYYFDNLIENLKLL 333
            |:|:::.|.:||||.:|.||.|||:||.||||.|:||...::|..:||||:|:|..|:.|:.|||
  Fly   734 MFQYESDGRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDYLIRWYHQNMKEHAKLL 798

  Fly   334 QYHRPLPKLKNLHASLFRNGLAAYMVVSKVLPVVMLDKTADANLESYISDE---SKMKNAMFTNP 395
            .|:..:|.||.|||.|.::.:.|...|...|.:.:...|.|...:|::.:|   ..::.|||:|.
  Fly   799 NYNGFIPSLKELHAILIQHPIFAAGTVLTTLSMCLNKTTDDFTTDSFLGNEENGKSLREAMFSNE 863

  Fly   396 KYVQVMTEVLPWLDNRGLLD 415
            :|...:..|:||::.|||||
  Fly   864 RYRANIERVMPWINRRGLLD 883

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31087	NP_001262952.1	EcKinase	52..335	CDD:281023	113/284 (40%)
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	113/285 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442519
Domainoid	1	1.000	57	1.000	Domainoid score	I17979
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12411
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.800