DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31087 and CG31288

DIOPT Version :9

Sequence 1:	NP_001262952.1	Gene:	CG31087 / 43062	FlyBaseID:	FBgn0051087	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_733094.1	Gene:	CG31288 / 318664	FlyBaseID:	FBgn0051288	Length:	428	Species:	Drosophila melanogaster

Alignment Length:	421	Identity:	136/421 - (32%)
Similarity:	229/421 - (54%)	Gaps:	32/421 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LPSWLSKISLEKAVQAQIGDFEKIISVIPQKGSSDGDNYSTQFLRLLVEVELIDHSTKDLSFVLK 81
            :|.|:::...|..:.....|..|::..........|:|:::..||:.:::|:.|.|.|..:::.|
  Fly    16 IPDWINEKYFESVLAKDEPDHVKVLKFTVVAAIPPGENFTSTMLRVYIKLEMKDGSVKTKTYIFK 80

  Fly    82 AQHSNEMMAAILAKLKLFQKEEQMYHSILPKFEKLYADAGKPIQFAPKAFKFDRDLGVDYILLED 146
            .....|...:.:.:..||.||..||.:.||.||.||.|.|..||.|||....:...|..:.:.||
  Fly    81 TMLPEERGGSDINEFGLFPKEAMMYKTYLPAFEALYKDVGWDIQLAPKCLHTEEREGDIHFIFED 145

  Fly   147 LHRKNFKNANRLAGLDLDHMHKVLEKLAAFHAASACYVEHHGLFGEEFTVGVFSESNRQLLQEFN 211
            |..|.|||.:|..|||::||.|.|:|||.:|||||.|.|.||.:..||:.|...:.    :::|:
  Fly   146 LCVKRFKNMDRTKGLDMEHMTKCLQKLAEYHAASAVYEELHGPYPSEFSEGFVKKD----VKKFH 206

  Fly   212 ASGAFLAQLKKWKNAQKIYEK------LADSDDYLV---------DRLLQDQQYNTREFNVLNHG 261
            ..|   .|||     :|.|:|      |.|:|.|:.         .:.|...:.|..||:|||||
  Fly   207 VDG---FQLK-----EKAYKKAMLSWGLKDADKYIKAFPTVKQYWAQCLSTLELNPDEFHVLNHG 263

  Fly   262 DCWANNVMYQHDAFGTIKETLFVDFQVGKYGSPANDLYYLILSSAAPELKTAKFDYLVRYYFDNL 326
            |.|::|:|..:...||:::.:.:|||:..:||||.||.:.:..|...:|:..:||:.||.|::.|
  Fly   264 DFWSSNLMSSYLPDGTLEKLILIDFQIVMWGSPAMDLLFFLTLSPTNDLRIKEFDHFVRIYWERL 328

  Fly   327 IENLKLLQYHRPLPKLKNLHASL--FRNGLAAYMVVSKVLPVVMLDKTADANLESYISDESKMKN 389
            :|.||:|:..:|||||::|..|:  ..:...|:..:...||:::.....|:|:.:..::..:.:|
  Fly   329 VECLKVLKLKKPLPKLRDLQNSMNNKNHSFYAFFSILNHLPIILFPTDKDSNIHNLSANTEEGEN 393

  Fly   390 ---AMFTNPKYVQVMTEVLPWLDNRGLLDLK 417
               .:.:||.:..||.::.|:|.|||:|:.:
  Fly   394 YRLRLLSNPAFGNVMKDLYPFLYNRGILNFE 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31087	NP_001262952.1	EcKinase	52..335	CDD:281023	108/297 (36%)
CG31288	NP_733094.1	EcKinase	50..331	CDD:281023	104/292 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442536
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I6344
Isobase	1	0.950	-	0	Normalized mean entropy	S12411
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.860