DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31087 and Y45G12C.4

DIOPT Version :9

Sequence 1:	NP_001262952.1	Gene:	CG31087 / 43062	FlyBaseID:	FBgn0051087	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_503696.1	Gene:	Y45G12C.4 / 189933	WormBaseID:	WBGene00021567	Length:	431	Species:	Caenorhabditis elegans

Alignment Length:	392	Identity:	82/392 - (20%)
Similarity:	148/392 - (37%)	Gaps:	101/392 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LEKAVQAQIGDFEKIISVIPQKGSSDGDNYSTQFLRLLVEVELID-HSTKDLSFVLKAQHSNEMM 89
            :|:|:||.:|...|..:....:..||...:.::.  .|:|.:.:. ...::|......:.|.::.
Worm    33 IEEAMQASLGTKAKFGANKSLRNISDLKGFQSKI--ALIEPDWVGAEKNQNLPSKFAVKISTQLA 95

  Fly    90 AAILAKLKLFQKEEQMYHSILPKFEKLYADAG-----KPIQFAPKAFKFDRDLGVD-YILLEDLH 148
            .|:.:|:..|                   |.|     :.::|..|..:...:..|: |.|||.|:
Worm    96 FAVFSKITKF-------------------DGGNGFGEEKLKFLGKFIREGHNREVEAYKLLEKLN 141

  Fly   149 R-----------KNFKNANRLAG---LDL---------------DHMHKVLEKLAAF--HAASAC 182
            .           |.||:...|.|   ||.               |.:..::..:|.|  |..|..
Worm   142 HPDIPHTKAYYLKPFKDKFDLKGFMILDFVPNVHPMPMYESIPADDLISLVRGVATFAGHGESLT 206

  Fly   183 YVEHHGLFGEEFTVGVFSE--SNRQLLQ-------EFNASG-AFLAQLKK----WKNAQKIYEKL 233
            ..:.....|.:....:|.|  .:.||.:       .|.|.. |.:.:..|    :||:.|.|.|:
Worm   207 AEQRSFARGSDIFELMFEEMYPDEQLERVCGVIQATFGAKNPAVVEECIKLFWIYKNSIKSYSKV 271

  Fly   234 ADSDDYLVDRLLQDQQYNTREFNVLNHGDCWANNVMYQHDAFGTIKETLFVDFQVGKYGSPANDL 298
            ::...:.:               ||||||.|.:|:::..|..|.:.....:|:|......|..||
Worm   272 SELLGFKL---------------VLNHGDLWQSNMLHCLDEHGNLVLKAIIDWQGVSMLPPGLDL 321

  Fly   299 YYLILSS-AAPELKTAKFDYLVRYY--FDNLIE----NLKLLQ--YHRPLP----KLKNLHASLF 350
            ..|::.. .|.|.:....:.|:.|:  |..::.    :|:.||  |:...|    .|..:.:|||
Worm   322 ARLLMGCLTAYERRERGAELLMLYHQTFTGIVGEELFSLEELQDSYNLYYPIMTLTLVPMVSSLF 386

  Fly   351 RN 352
            .|
Worm   387 EN 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31087	NP_001262952.1	EcKinase	52..335	CDD:281023	67/343 (20%)
Y45G12C.4	NP_503696.1	DUF1679	16..422	CDD:369592	82/392 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810