DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31370 and AgaP_AGAP003762

DIOPT Version :9

Sequence 1:	NP_733095.2	Gene:	CG31370 / 43060	FlyBaseID:	FBgn0051370	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_559537.2	Gene:	AgaP_AGAP003762 / 3290900	VectorBaseID:	AGAP003762	Length:	405	Species:	Anopheles gambiae

Alignment Length:	416	Identity:	117/416 - (28%)
Similarity:	192/416 - (46%)	Gaps:	51/416 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DQLNVPEWLNEQFVTDVLRSHEKEPDLRVTK-LDFTPGSAKGDNYASVIIRARVEYITQKGFFSK 71
            |:|..|.|||::|..||:|....:|.:.:.| ....||:.|||:||||:.|..|.|.:|:....:
Mosquito     6 DELEAPGWLNDEFFRDVMRESNNDPTIELIKPCVLRPGTNKGDHYASVMFRTTVRYRSQRSSKEQ 70

  Fly    72 S--LIIKT-------VLEMFAGSALFKTEIGMYRKVLPEFARILRENNDTSRLYAECIYYSLEPS 127
            |  :|:||       ..|:.....||..||.||.|||||..|:|:|..:..: |...||.:|:|.
Mosquito    71 SVNIIMKTKPEADGLKKELLDDDRLFAIEIEMYSKVLPEMTRMLKEIGEEYK-YPRYIYGALKPR 134

  Fly   128 QVMIFEDLGEMDYAMVRDRVLTHGEICGAYSKLAKFHALSMKIINERPEFVKEFKDGICLVDIPY 192
            .::|.||:.:..:.|. :.:.|..::......:|.|||.|:.:.:....||......|.
Mosquito   135 TILILEDISDQGWVMA-EFISTLDDMKPIVKDIAMFHAASVMLESADSTFVARHNYSIA------ 192

  Fly   193 MSSGMGPFKDFL----GRIPELDRYKTHFEKIEVHF---IDRLRDIMKEYQTNPQPGYY------ 244
             ...|| ||..:    |.:..|.|..:.|    .||   :.|.::.:..:.|    ..|
Mosquito   193 -EKFMG-FKGMITKGFGDLMHLTRTCSEF----AHFARPLGRFQENLHNFFT----ALYIPSKTI 247

  Fly   245 --VLCHGDYHTRNIMVKHNKESGGFEDCMLLDYQGCYVAPLAFDLMYSIYMLMNREQRIGELETL 307
              ||.|||:|::|::.:.:.| |...:.:|||||.|.....|.||.|.:.|:..:|.:......|
Mosquito   248 QNVLIHGDFHSKNMLHQVDVE-GRHTNTILLDYQICCWTSPAVDLYYLLDMIPTQEVKDKYRSEL 311

  Fly   308 LNYYFSVLRETLRKIGYQGKLPDPPAFWKEMYR---LKDYEFLFLSTYLPM-SVGLSLETATNEE 368
            :..|:....:.|:::||.||:|.......|:.|   |:.:.:...|::..| ...:.:|.....|
Mosquito   312 IYMYYQQYSDLLKRLGYVGKIPSLLDLQIELVRYAGLELFHYAMFSSFRYMDQTAIDIEAYLKGE 376

  Fly   369 TDDKL---QDFIEECKSILARFERSG 391
            .::..   .:|.:...|.|.||...|
Mosquito   377 LENPAFNNPEFKKLMHSELTRFLHQG 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31370	NP_733095.2	EcKinase	47..324	CDD:281023	85/300 (28%)
CG31370	NP_733095.2	APH	<202..320	CDD:279908	32/132 (24%)
AgaP_AGAP003762	XP_559537.2	PKc_like	46..328	CDD:304357	85/300 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D279272at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11012
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.890