DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31370 and AgaP_AGAP003763

DIOPT Version :9

Sequence 1:	NP_733095.2	Gene:	CG31370 / 43060	FlyBaseID:	FBgn0051370	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_310302.5	Gene:	AgaP_AGAP003763 / 1271496	VectorBaseID:	AGAP003763	Length:	404	Species:	Anopheles gambiae

Alignment Length:	410	Identity:	103/410 - (25%)
Similarity:	184/410 - (44%)	Gaps:	33/410 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DQLNVPEWLNEQFVTDVLRSHEKEPDLR-VTKLDFTPGSAKGDNYASVIIRARVEYITQKGFFSK 71
            |:|:.|||||:.:...||...|.:.:.| :......||:..||::|||:.|..::|      :..
Mosquito     6 DELSSPEWLNDDYFRHVLCKIECDSNARLIGACVLRPGTKAGDHFASVMYRTTLQY------YCT 64

  Fly    72 SLIIKTV--------------LEMFAGSALFKTEIGMYRKVLPEFARILRENNDTSRLYAECIYY 122
            :.:.||:              .::..|...|..||.||.:|||:.|.::| |......|.:.::.
Mosquito    65 ANVKKTINLIMKIKPDTDGFKKDLLDGDDFFGKEIRMYTEVLPQMAALMR-NIGEEYQYPKLVFA 128

  Fly   123 SLEPSQVMIFEDLGEMDYAMVRDRVLTHGEICGAYSKLAKFHALSMKIINERPEFVKEFKDGICL 187
            |..|..::|.||:....:.| ...:.:..|:......:|||||.|:.:..:.|.|..:::..|..
Mosquito   129 SHVPHTIIILEDVSSQGWTM-EGLIKSFSELEPTIDAIAKFHAASVVLQEKDPTFASQYQCTIAK 192

  Fly   188 VDIPYMSSGMGPFKDFLGRIPELDRYKTHFEKIEVHFIDRLRDIMKEYQTNPQPGYYVLCHGDYH 252
            :.........|.|:.|:..:.|....:.....:| ||..::.|:::......:....||.|||:|
Mosquito   193 ILCSMRGMTDGCFRSFISFLSETAELQEFVAPVE-HFHAKIDDVLQAAYAPSETFANVLIHGDFH 256

  Fly   253 TRNIMVKHNKESGGFEDCMLLDYQGCYVAPLAFDLMYSIYMLMNREQRIGELETLLNYYFSVLRE 317
            .:|::  |.:.:|...|.:.:|||.|.......||.|..||:..:..:....:.::..|......
Mosquito   257 FKNLL--HLQLAGKIVDTIFVDYQMCSWCSPVVDLYYLTYMIPEQSVKNAHRDEIIYRYHQKFAS 319

  Fly   318 TLRKIGYQGKLPDPPAFWKEMYRLKD---YEFLFLSTYLPMSVG-LSLETATNEETDD---KLQD 375
            .||::.|:|::|.......|:.|..|   |.::..|.:|...:. :..|......||:   |:::
Mosquito   320 LLRRLNYRGRVPTLTELQVELLRKADLELYHYIVFSAFLHTDLSKVDSEAFFLGRTDNPALKMEE 384

  Fly   376 FIEECKSILARFERSGYFEN 395
            |.|..|..|.||...|..||
Mosquito   385 FKETMKIELKRFLYHGIIEN 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31370	NP_733095.2	EcKinase	47..324	CDD:281023	68/290 (23%)
CG31370	NP_733095.2	APH	<202..320	CDD:279908	26/117 (22%)
AgaP_AGAP003763	XP_310302.5	PKc_like	47..326	CDD:304357	68/289 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D279272at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11012
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.890