DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31370 and AgaP_AGAP013346

DIOPT Version :9

Sequence 1:	NP_733095.2	Gene:	CG31370 / 43060	FlyBaseID:	FBgn0051370	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_003436599.1	Gene:	AgaP_AGAP013346 / 11176019	VectorBaseID:	AGAP013346	Length:	422	Species:	Anopheles gambiae

Alignment Length:	345	Identity:	94/345 - (27%)
Similarity:	153/345 - (44%)	Gaps:	46/345 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DQLNVPEWLNEQFVTDVLRSHEKEPDLRVTK-LDFTPGSAKGDNYASVIIRARVEY----ITQKG 67
            |....|.|||::|..||:|....:..:.:|. ....||::|.|:|.||:.|..|.|    :|::.
Mosquito     6 DHPEAPAWLNDEFFRDVMRESNNDSSIELTSACILRPGTSKKDHYGSVMFRTTVTYQSKRVTEEK 70

  Fly    68 FFSKSLIIKT-------VLEMFAGSALFKTEIGMYRKVLPEFARILRENNDTSRLYAECIYYSLE 125
            |.  .||:||       :.::.....||..||.||.|||||..|:|:|..:..: |...||.:|:
Mosquito    71 FV--DLIMKTKPEADGLMKDLLDDDGLFVVEIEMYSKVLPEVTRLLKEIGEEYK-YPRYIYGTLK 132

  Fly   126 PSQVMIFEDLGEMDYAMVRDRVLTHGEICGAYSKLAKFHALSMKIINERPEFVKEFK-------- 182
            |..::|.||:....: :..|.:.|..::......:|..||.|...:      |.:|:
Mosquito   133 PHTILILEDISGQGW-VEGDLINTLDDMKPIVKNVAMLHAASDTTV------VTKFRHTMAHKFL 190

  Fly   183 --DGICLVDIPYMSSGMGPFKDFLGRIPELDRYKTHFEKIEVHFIDRLRDIMKEYQTNPQPGYYV 245
              :|:       :..|.|.........||.    ..|.|..|.|...|||.........:....|
Mosquito   191 GLEGL-------VRKGFGDLMQLTELYPEF----AQFAKPLVKFQQNLRDFFDSIFKPTKSIQSV 244

  Fly   246 LCHGDYHTRNIMVKHNKES-GGFEDCMLLDYQGCYVAPLAFDLMYSIYMLMNREQRIGELETLLN 309
            |.|||.||:|::  |..:: |...:.:|||||.|.....|.||.|.:.::..:|.:......|::
Mosquito   245 LIHGDCHTKNLL--HQLDAHGRHTETILLDYQICCWTSPAIDLYYMLDLIPTQEIKDNYRSELVH 307

  Fly   310 YYFSVLRETLRKIGYQGKLP 329
            .|.......|:::|::..:|
Mosquito   308 LYHQQYSNLLKRLGFKRNIP 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31370	NP_733095.2	EcKinase	47..324	CDD:281023	80/298 (27%)
CG31370	NP_733095.2	APH	<202..320	CDD:279908	32/118 (27%)
AgaP_AGAP013346	XP_003436599.1	PKc_like	48..322	CDD:304357	79/296 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D279272at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11012
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.890