DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31370 and AgaP_AGAP012971

DIOPT Version :9

Sequence 1:	NP_733095.2	Gene:	CG31370 / 43060	FlyBaseID:	FBgn0051370	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_003436595.1	Gene:	AgaP_AGAP012971 / 11175866	VectorBaseID:	AGAP012971	Length:	858	Species:	Anopheles gambiae

Alignment Length:	400	Identity:	111/400 - (27%)
Similarity:	190/400 - (47%)	Gaps:	48/400 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SLADQLNVPEWLNEQFVTDVLRSHEKEP--DLRVTKLDFTPGSAKGDNYASVIIRARVE---YIT 64
            |.:..::||||:.:::..|.:.....:|  |..:|.||....:..||||||::.|.||.   :.|
Mosquito     4 SASAAVSVPEWMTKEYFVDAIAVKLGKPATDFTITDLDVRRATEAGDNYASILYRVRVSVRLHNT 68

  Fly    65 QKGFFSKSLIIKTVL------EMFAGSALFKTEIGMYRKVLPEFARILRENNDTSRLYA-ECIYY 122
            .......|||:|.:.      ||.....||..||.||..|||...::..:...||..:. .|:.:
Mosquito    69 DGTPMDISLIVKALPKLSLTDEMVKLMNLFPKEIAMYTDVLPRLEQLYHQAGRTSVHFGPRCLKH 133

  Fly   123 SLEPSQVMIFEDLGEMDYAMVRDRV---LTHGEICGAYSKLAKFHALSMKIINERPEFVKEFKDG 184
            |.||:.|::.|||.|..:.|...|.   :.|..:  ...::|:|||.|:.:.:.|..:.:.|::|
Mosquito   134 STEPTDVIVLEDLRERQFTMANRRQGLDMEHTRL--VLRRMAQFHAASVVLEDHRGPYGELFREG 196

  Fly   185 ICLVDIPYMS----SGMGPFKDFLGRIPELDRYKT-HFEKIEVHF-IDRLRDIMKEYQTNPQPGY 243
            :.......||    .|..   ||..:|......|. |...:..|: :|....:::..:.| :.|:
Mosquito   197 MFTEKGRAMSEQFQKGQA---DFFQKIMRCWSEKAQHCASVMQHWGMDLFDSLIRVTRAN-RKGF 257

  Fly   244 YVLCHGDYHTRNIMVKHNKESGGFEDCMLLDYQGCYVAPLAFDLMYSIYMLMNREQRIGELETLL 308
            .||.|||....||:.::|::| ...|.:|:|||..:.|..|.||:|.::..:|.:.::.::..|:
Mosquito   258 NVLNHGDMWCNNILFQYNEDS-TVNDILLIDYQLSFWASPAIDLIYFMFTSVNGDFKLSQMNYLV 321

  Fly   309 NYYFSVLRETLRKIGYQGKLPDPPAFWKEM------YRLKDYEFLFLSTYLPMSVGLSLETATNE 367
            .||...|.::|:.:||.|.:|    ..||:      :.|..|...|  :.||:.:        .|
Mosquito   322 QYYHEHLVDSLKFLGYTGTVP----LLKELHSDIISHHLFGYMICF--SILPICL--------ME 372

  Fly   368 ETDDKLQDFI 377
            :|||...|.:
Mosquito   373 KTDDASMDLM 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31370	NP_733095.2	EcKinase	47..324	CDD:281023	84/295 (28%)
CG31370	NP_733095.2	APH	<202..320	CDD:279908	33/119 (28%)
AgaP_AGAP012971	XP_003436595.1	EcKinase	49..337	CDD:281023	84/294 (29%)
		EcKinase	478..765	CDD:281023
		Adenylation_DNA_ligase_like	<776..811	CDD:299865
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810