DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31097 and CG10562

DIOPT Version :9

Sequence 1:	NP_733093.2	Gene:	CG31097 / 43058	FlyBaseID:	FBgn0051097	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_651385.3	Gene:	CG10562 / 43066	FlyBaseID:	FBgn0039326	Length:	405	Species:	Drosophila melanogaster

Alignment Length:	413	Identity:	117/413 - (28%)
Similarity:	208/413 - (50%)	Gaps:	28/413 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VPKWLNKSKFESLIAKDEPDFTKIDQFTTVAAVPPGGNFASVMLRVYLDIVMKDGSQKRKSYVVK 76
            :|.|:....||.|:..:...::||..|........|.|:|::||||.:::.::||..|..||:||
  Fly     6 IPDWVTAEIFEDLLKANVDGYSKIKNFKADIGSAAGENYATIMLRVKIEVELQDGKSKSVSYMVK 70

  Fly    77 TMLESDKGGKAVNEM----RYFHKEQQMYSTYLPQFEKIYRVAGHPVQLMPKCLEIGEIDGNIYF 137
            ...:.:    |:.||    ..|..|:.||:..:|:.|.:|:..|..:....|..::.....: |.
  Fly    71 LPHQVE----AIQEMMKRTNIFEIERTMYNEVVPELEALYKAVGVDITFGAKNYDLKNAKTD-YV 130

  Fly   138 IFEDLSTRNFVAADRTKGVNMEHMRLSLRKLAELHAASVIYKERYGPYHADFDNGFARKDKIEHS 202
            ..|||..:.|..|:|.:|::.||....||||::.||||.:.....|||......||.:::.....
  Fly   131 ALEDLGLKGFKNANRLEGLDQEHTERVLRKLSQWHAASAVRVATKGPYPKILLQGFFKEESRPVM 195

  Fly   203 VRRFEVKAPEYKAAMKTWGIDECYLKNFPTTEQYG--KLCLESLNVDPQDFNVLTHGDFSPSNIL 265
            ....:.....:..:..|:...|.||......:...  |: .|...|:|.:||||.|||...:||:
  Fly   196 SEMIKGMGANFVKSCATYEGHEAYLDKVKALQPVAIDKI-FEFAKVEPTEFNVLNHGDSWSNNIM 259

  Fly   266 FKYNENGAPSEALILDFQICKWASPTQDLLMLIILSARKDSSYKEFDNIVRIYWEYLIDFLRVLK 330
            |:|:..|...|..::|:|:.|:.:..||||..::.|.:.:....:||..::||.:.|::.|::||
  Fly   260 FQYDAFGKIKEVYLVDYQLPKYGTVAQDLLYFLLSSTKLEDKLAKFDYYIKIYHDNLVEHLKILK 324

  Fly   331 YKKPLPQLRELQSAIYKKNN-TFSAFFAVMNHL---PGDLLPVCKENNLHTFNLEDEVGKS-FRT 390
            |.||:|.||::..|::|... .::....||:.:   |.|           :.:||:.:|.| |:.
  Fly   325 YSKPIPSLRDIHLALFKYGYFGYTVATGVMSAVLLDPTD-----------SASLENFIGGSDFQM 378

  Fly   391 KVYTNPIFVEVVKELYPICCNRG 413
            ::|.:|.:.:.::.:.|...|||
  Fly   379 QLYNSPRYRKHIQAVMPWLLNRG 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31097	NP_733093.2	EcKinase	46..331	CDD:281023	85/290 (29%)
CG10562	NP_651385.3	EcKinase	41..325	CDD:281023	85/289 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442498
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I6344
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	7.000