DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11893 and CG6834

DIOPT Version :9

Sequence 1:	NP_651375.1	Gene:	CG11893 / 43056	FlyBaseID:	FBgn0039316	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster

Alignment Length:	427	Identity:	111/427 - (25%)
Similarity:	189/427 - (44%)	Gaps:	46/427 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PENADTEQFNADELEAPAWLNAQFITDVLRTYEKCPELEVTDLKI-----TPASAQGDHYASVMF 61
            ||...:||....:.:...|||.....:|:.:.|  ||.:    ||     :.|:..||::||.:.
  Fly   480 PETPSSEQPENPKNQILDWLNVSDFAEVISSAE--PEFD----KIVGGSWSSATKPGDNFASKLL 538

  Fly    62 RTTAEYTTSKGKFCKPL--IIKTMPEQEGHKKDMLSDSHLFSTEINAYTKALPEFERILREAGDD 124
            :...| |..|....|..  |:|..|:.   ..|..:|.::|..|:..|.|.:|.||::.::|| .
  Fly   539 KIDIE-TQLKDHTSKTFSYILKVQPKS---TPDNFTDVNMFPKEMEMYQKYVPAFEQLYKDAG-L 598

  Fly   125 TKLFV--PCIYHSLEPRQVLIFEDLVPQGYFVIRDR--PINMNEYKNVFSKLAKWHAVSMKV--L 183
            |..|.  ..:.:.....:.|:.|:|..:| |.:.||  .:||...|:...|||:|||.|:|.  |
  Fly   599 TVTFTANSFVLNKAVKEEYLLMENLQTKG-FKMADRMKGLNMEHTKSSLKKLAQWHAASIKYKEL 662

  Fly   184 N-EQPDILKDFKYGLMEMPSIMSDPMVTTGMDNFLKMMDQIPELTKYKPHFEKIKENYIQRMGDV 247
            | ..|.:..|..|  :|....:...|..:..:.::::........:|.|..|.|.:|::.:   |
  Fly   663 NGAYPPLYNDGIY--IEQTRDVFHNMFASAKEAYIRIFGTFEGADEYLPKLEWIIDNHVDQ---V 722

  Fly   248 MQEYRKNVQSDGYYVMCHGDFHGRNMMF-----NKNEEVMFVDFQICNLCPITIDLSYSVYMLME 307
            :::.:.|.|:  :.|:.|||....|:||     .:.:|...:|.|.........||.|.:....|
  Fly   723 LEDAKINEQA--FNVLNHGDAWINNIMFQYDAEGRLKETYLLDHQNAKYGNPAQDLYYFLISSAE 785

  Fly   308 PEQRWDLGKDLINFYFSVLEDTLKKVGYKGKMPTNDGLWKQIHRHKFYDFFLLTTFSPMIVAVKA 372
            .:.:.|...:||.||...|.:..|.:.|.|.:|:...|...:..|.  .|.:.|..|.:.|.:..
  Fly   786 LDIKVDEFDNLIRFYHENLVEHTKLLKYNGFVPSLSELHAILIEHP--AFAVGTVISTLTVCLTD 848

  Fly   373 NTFKIHEL--IQDPE---IRQKSYLYDPYVQDVKKLL 404
            ..|. .||  ::.||   .|.|....:.|...|:|::
  Fly   849 EGFN-PELFFVETPESEAFRTKLLGNERYKAHVEKIM 884

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11893	NP_651375.1	EcKinase	52..335	CDD:281023	78/296 (26%)
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023	78/296 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459812
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840