DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11893 and dhs-27

DIOPT Version :9

Sequence 1:	NP_651375.1	Gene:	CG11893 / 43056	FlyBaseID:	FBgn0039316	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_508591.3	Gene:	dhs-27 / 180632	WormBaseID:	WBGene00000990	Length:	320	Species:	Caenorhabditis elegans

Alignment Length:	251	Identity:	49/251 - (19%)
Similarity:	81/251 - (32%)	Gaps:	94/251 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 DILKDFKYGLMEMPSIMSDPMVTTGMDNFLKMMDQIPELTKYKPHFEKIKENY-IQRMGDVMQEY 251
            |.|||            :..::|.|.|...|.  .|.||.|.:    .:|:.| |.|..|.:...
Worm    44 DYLKD------------TWTVITGGTDGIGKA--YIEELCKTR----GLKKFYLIGRNIDKLNNT 90

  Fly   252 RKN-VQSDGYYVMCH-GDFHGRNM-MFNKNEEVMFVDFQI--CNLCP-----------------I 294
            :|. |:..|..|||| .||...:: ...|:.|.:.|...|  ..:.|                 :
Worm    91 KKELVEQHGCEVMCHVHDFEKDDLSALPKDLETLDVGILINCAGIAPHIIGTLTELPEGLASKIL 155

  Fly   295 TIDLSYSVYML------MEPEQR--------------------WDLGKDLINFYFSVLEDTLKKV 333
            .::|..:|.|.      |..::|                    :...|..::|:...|.|..:..
Worm   156 RVNLMSAVKMTEMILPNMVKKKRGIIVNISSMTGWRPLPYLSSYPASKAALSFFSDSLSDEYRGT 220

  Fly   334 GYKGKMPTNDGLWKQIHRHKFYDFFLLTTFSPMIVAVKANTFKIHE----LIQDPE 385
            |.:                       :....||:||.|..:::..|    .:..||
Worm   221 GIR-----------------------VQCLIPMLVATKVASYEAEEANNIFVVTPE 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11893	NP_651375.1	EcKinase	52..335	CDD:281023	40/195 (21%)
dhs-27	NP_508591.3	17beta-HSD1_like_SDR_c	48..294	CDD:187614	46/247 (19%)
dhs-27	NP_508591.3	adh_short	50..234	CDD:278532	40/212 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910