DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13658 and CG6834

DIOPT Version :9

Sequence 1:	NP_651374.2	Gene:	CG13658 / 43055	FlyBaseID:	FBgn0039315	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster

Alignment Length:	418	Identity:	103/418 - (24%)
Similarity:	184/418 - (44%)	Gaps:	24/418 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 PAWLNAELIEGALRAYEKDPELHVTDLKISPATLQGDHYASVMFR-AVSHYSTAKGNFSKALIVK 81
            |.|||....|..|.|: .|....:...::.||...|::||::|.| ::....|.|.......::|
  Fly    62 PEWLNQTQFEELLAAH-VDQFSKIVGFQVKPAMAPGENYATLMLRISIDVELTDKSTKLVCFMLK 125

  Fly    82 TMPEQEGHKKDMLSNSPIFKTEILMYSKALPELERILREAG-DTTKLYAPCIY---HSLEPH--Q 140
             :|......:.||:.:..|.:|..:||..||:||.:.:..| |.|  :||..:   ...||.  .
  Fly   126 -VPHNVPQMEQMLAMANFFNSENKVYSDILPKLEELYKAKGLDIT--FAPKAFKLDSVKEPKLAN 187

  Fly   141 VMIFEDLVPQGY-TVIRDRYPNKEELQKAFFKLAKWHAASMKVLNERPDFLKEFKYGLWGMPNFL 204
            .::..||...|: .:.|....|.|:.:.|..|||::||||...:.....:..:|..|:.|....:
  Fly   188 TVLMSDLSQDGFKNLNRLECLNLEQTKFALKKLAQFHAASSMNVQVNGPYEDQFVNGVMGGNKEV 252

  Fly   205 NDSIVTTGVPCFLEMLDKVPELTKYK---PYFEKIKDNYIQQMSAVMEEYRTNPKPNRYYVLCHG 266
            ..:.....|..|...|  :..|..:|   .:.||::..::|..  :..|:.....|:.:.||.||
  Fly   253 LMAFYEGMVASFRTAL--MANLKNFKNGEEFREKLEKAFVQIF--LDFEHLMTADPDEFNVLNHG 313

  Fly   267 DFHGRNMMFRYNKETGSFEDVMLVDFQISNVCPLSIDLIYSIFMVMDTEDRWDLGKEYINYYFSV 331
            |....|::|:.:.: |..:|::.||||.......:.||.|.|...:..:.:.|..:.:|.:|...
  Fly   314 DCWMNNLLFKLDSK-GEVQDMLFVDFQNPKYGSPTQDLFYLILTSVHIDYKLDYFEYFIRHYHEQ 377

  Fly   332 LADTLKKIGFKGEMPTQTGVWEHIHGHKDYEFFMMTSFLPLVA--AMNTKTFKSM--DSFFDPQT 392
            |...|..:||.|:.|:...:...::.|..:..|.....||:|.  ...:.||::.  ||....:.
  Fly   378 LTQHLDLLGFTGKQPSLRELHMLMYKHGSWAVFPSIGVLPIVLLDPNESATFENFLGDSESSAKF 442

  Fly   393 KQKSFFLDEYITDVKMLLRKFEELGYFK 420
            |...:....|...::.||...:..|:.:
  Fly   443 KNLLYTNKRYHGYIEKLLPWLDNKGFLE 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13658	NP_651374.2	EcKinase	52..341	CDD:281023	75/299 (25%)
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	75/299 (25%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459813
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840