DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10514 and CG6830

DIOPT Version :9

Sequence 1:	NP_651371.1	Gene:	CG10514 / 43052	FlyBaseID:	FBgn0039312	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster

Alignment Length:	425	Identity:	118/425 - (27%)
Similarity:	202/425 - (47%)	Gaps:	33/425 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PEWLTHEYIEHALRCHYKDEGLTITQLQINPALGPGENYGGVLTRARVEFTLSNKEKNVQNLIVK 69
            |:||.....|..|.... |:...|...::.||:.|||||..::.|..::..|::|...:.:.::|
  Fly    47 PKWLNQTQFEELLAADV-DQFSKIVGFRVKPAMAPGENYATLMLRISIDVELTDKSTKLVSFMMK 110

  Fly    70 TEIDDDELTQELMAPYDIYNREMTIYQEVLPKCRELLNEIGDTERIFPTAIYVDRER-----MAI 129
            ...|..:: :::|:..:.:..|...|.|:|||..||....|...:..|.|..:|..:     ..:
  Fly   111 VPHDTPQM-EQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRAFKLDATKEPKVANTV 174

  Fly   130 IFEDLSVVGYVMADRVRRLNEEHTHLILRKLAKFHAATAVLNERQSGCLESYDRGFFNRYTNAYS 194
            :..||...|:...:|:..||.|.|...|.:||:||||.|.:.:......:.:..|.......|..
  Fly   175 LMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPYPDIFVNGVMGNNKEAII 239

  Fly   195 GYFVGGLLAAARW-----MSKVPTLAHYGEK----LFALAPHYMDIGRECFAPTPGQVNVLAHGD 250
            . |:.|:||:.|.     :.|......|.||    |..|...:|.:|    ...|.:.|.|.|||
  Fly   240 A-FMEGMLASFRTSFMANLDKFKNGEEYREKLEKALAGLTMEFMKLG----IVDPNEFNALNHGD 299

  Fly   251 VWTNNVMFKYDPNTGRPVDVLLIDFQYSFWGSPCIDLHHLFNTSLKEPLRRDQQNGLFQFYHKIF 315
            .|.||::||.: ::|...|::.:|||...:|||.:||.:...:|    ::.|.:...|.|:.:.:
  Fly   300 CWMNNLLFKMN-SSGDLEDMVFVDFQNPKYGSPAMDLLYFIISS----VQIDYKLSHFDFFIRHY 359

  Fly   316 TETLEK----LNYRQNQIPSLHQFKLEVEQKRFFALHSTVVVQPVMISQDPT-DACFNALMNDDE 375
            .|.|.|    |.:...: |||.:....:.:...:.|..|:.|.|::: .||| .|.|:..|:|..
  Fly   360 QEALVKHLGILGFTGRK-PSLRELHRTLIKYGGWVLFPTISVLPLVL-LDPTQSATFDNFMSDSA 422

  Fly   376 RGIRFKNRLYNNPTVQQNLHSLVPFFDRKGLLEVN 410
            .|:.|:..||.|...|:.:..::|:.|.:|.|||:
  Fly   423 DGVSFRGSLYANKRCQEYIERILPWLDNRGFLEVS 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10514	NP_651371.1	EcKinase	39..324	CDD:281023	83/302 (27%)
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	83/302 (27%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459452
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850