DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10514 and CG33511

DIOPT Version :9

Sequence 1:	NP_651371.1	Gene:	CG10514 / 43052	FlyBaseID:	FBgn0039312	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001014492.2	Gene:	CG33511 / 3346223	FlyBaseID:	FBgn0053511	Length:	415	Species:	Drosophila melanogaster

Alignment Length:	362	Identity:	78/362 - (21%)
Similarity:	157/362 - (43%)	Gaps:	45/362 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 CH---------YKDEGLTITQLQINPALGPGENYGGVLTRARVEFTL-SNKEKNVQNLIVKTEID 73
            ||         .|.:.:.:...|::........|.|...:..:|..: .:|:|...|..:|:...
  Fly     9 CHLIAQRTLSVVKKDNVILINSQVDAGSKDLMGYMGEYYKLHLEAEVKGDKKKYFLNYFIKSLPR 73

  Fly    74 DDELTQELMAPYDIYNREMTIYQEVLPKCRELLNEIGDTERIFPTAIYVDRERMAIIFEDLSVVG 138
            .:|..:|......::.:|..:|.::|||.::..     |::::|...|...:  .::.|||:
  Fly    74 KNEPQREECERKGVFQKESALYSQILPKIQKYA-----TKKLYPKCYYSRND--ILVLEDLT--- 128

  Fly   139 YVMADRVRRLNE----EHTHLILRKLAKFHAATAVLNERQS-GCLESYDRGFFNRYTNAYSGYFV 198
              ...|..|.||    :|..::|..|::.|||:....|::: ...|||.......:.::.:.:::
  Fly   129 --QDYRHLRANEYYTLDHYKIVLEHLSELHAASIAWEEKENVKIYESYKNVLIELHLDSNNSWYI 191

  Fly   199 GGLLAAARWMSKVPTLAHY---------GEKLFALAPHYMDIGRECFAPTPGQVNVLAHGDVWTN 254
            .||.|.....::.|   |:         .:||:.|    :....|..||:....|||.|.|.|.:
  Fly   192 TGLKAIVFLAARNP---HFQTMKAQNFIQDKLYNL----LTKAEELVAPSKTIRNVLCHRDTWDH 249

  Fly   255 NVMFKYDPNTG-RPVDVLLIDFQYSFWGSPCIDLHHLFNTSLKEPLRRDQQNGLFQFYHKIFTET 318
            |:::.::..:. .|....::|||.:.:.||.:|:..|........:||...:...:.|:|.....
  Fly   250 NIVYYFNKESSVLPNACCIVDFQLTQYCSPTLDVLFLLYIVASAEVRRAIYDECLEHYYKNLQHH 314

  Fly   319 LEKLNYRQNQIPSLHQFKLEVEQKRFFALHSTVVVQP 355
            |::|...:|.|.. :.|:.|.::.|..||....:.:|
  Fly   315 LDRLGLDKNLITE-NNFRKECQRTRLAALVIWALTEP 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10514	NP_651371.1	EcKinase	39..324	CDD:281023	66/300 (22%)
CG33511	NP_001014492.2	PKc_like	41..319	CDD:304357	65/296 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459513
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940