DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10513 and CG11893

DIOPT Version :9

Sequence 1:	NP_651370.2	Gene:	CG10513 / 43051	FlyBaseID:	FBgn0039311	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_651375.1	Gene:	CG11893 / 43056	FlyBaseID:	FBgn0039316	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	431	Identity:	119/431 - (27%)
Similarity:	199/431 - (46%)	Gaps:	44/431 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EQGKEDATEFHPAPEWLDETYLERLLRDLKNDPGLRITDLVIKPATAKGDNYASVMTRVRILFLK 67
            ||...|..|   ||.||:..::..:||..:..|.|.:|||.|.||:|:||:|||||.|....:..
  Fly     8 EQFNADELE---APAWLNAQFITDVLRTYEKCPELEVTDLKITPASAQGDHYASVMFRTTAEYTT 69

  Fly    68 SGAK--SPETEYYIVKTTYENDAFASGIFSQYQVSTTEMRMYEKILPQLSSLIEKTRQPEKVFAK 130
            |..|  .|    .|:||..|.:.....:.|...:.:||:..|.|.||:...::.:.....|:|..
  Fly    70 SKGKFCKP----LIIKTMPEQEGHKKDMLSDSHLFSTEINAYTKALPEFERILREAGDDTKLFVP 130

  Fly   131 TLHVDYE-HEAIIFEDLAVTKY-VLADRLVGFDLEHTRLGLRKLAKMHAAA-AVLNERQPGLLTK 192
            .::...| .:.:|||||....| |:.||.:..: |:..: ..||||.||.: .|||| ||.:|..
  Fly   131 CIYHSLEPRQVLIFEDLVPQGYFVIRDRPINMN-EYKNV-FSKLAKWHAVSMKVLNE-QPDILKD 192

  Fly   193 FDHGIFNRHTQAFAPFFVNTVGVAADFARECPELGERYATKLKKLQER--------VMEYSTRVY 249
            |.:|:....:....|.....:........:.||| .:|....:|::|.        :.||...|
  Fly   193 FKYGLMEMPSIMSDPMVTTGMDNFLKMMDQIPEL-TKYKPHFEKIKENYIQRMGDVMQEYRKNV- 255

  Fly   250 DPQPGDFNTLVHGDYWVNNVMLRYGENKEPLDMTLIDFQFCSWSSPAVDLHYFFNTSVQVDIRYE 314
              |...:..:.|||:...|:|  :.:|:|   :..:|||.|:.....:||.|.....::.:.|::
  Fly   256 --QSDGYYVMCHGDFHGRNMM--FNKNEE---VMFVDFQICNLCPITIDLSYSVYMLMEPEQRWD 313

  Fly   315 QQDALFQYYHTVLVETLKDLNFGGYIPTLRQFVLQLERGRFF----AVTVALVCQAILTNDQNAD 375
            ....|..:|.:||.:|||.:.:.|.:||......|:.|.:|:    ..|.:.:..|:..|    .
  Fly   314 LGKDLINFYFSVLEDTLKKVGYKGKMPTNDGLWKQIHRHKFYDFFLLTTFSPMIVAVKAN----T 374

  Fly   376 ADFNALMKDDERGRNFRKVLYTNKRLQDNLKRELPRFDRSG 416
            ...:.|::|.|    .|:..|.......::|:.|.:::..|
  Fly   375 FKIHELIQDPE----IRQKSYLYDPYVQDVKKLLGKYEEMG 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10513	NP_651370.2	EcKinase	50..336	CDD:281023	83/298 (28%)
CG11893	NP_651375.1	EcKinase	52..335	CDD:281023	83/298 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459574
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850