DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10513 and CG9498

DIOPT Version :9

Sequence 1:	NP_651370.2	Gene:	CG10513 / 43051	FlyBaseID:	FBgn0039311	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_609015.2	Gene:	CG9498 / 33885	FlyBaseID:	FBgn0031801	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	436	Identity:	115/436 - (26%)
Similarity:	186/436 - (42%)	Gaps:	62/436 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 PEWLDETYLERLLRDLKNDPGLRITDLVIKP-----ATAKGDNYASVMTRVRILFLK--SGAKSP 73
            ||:|:|.:....|.:     |||.:.:.:|.     .:..||||.|.:.||.:.|.:  .|.:||
  Fly    13 PEYLNEHFFTETLEE-----GLRESKVTLKEINFAWGSNPGDNYCSAIYRVGVSFARWADGGESP 72

  Fly    74 ETEY--YIVKTTYENDAFASGIFSQYQVSTTEMRMYEKILPQLSSLIEKTRQPEKVFAKTLHVDY 136
            .||.  .||||....:  |:.......|...|.:.|..:||:|..|..         ..|....|
  Fly    73 VTEQLSLIVKTIPITE--ATQFLEDVCVFIKEKQTYTDVLPRLDILSR---------GDTFGAKY 126

  Fly   137 EH------EAIIFEDLAVTKYVLADRLVGFDLEHTRLGLRKLAKMHAAAAVLNERQPGLLTKFDH 195
            .|      :.|:|.||.|..:.:|.|..|.|..|..|.|::|.|.||.:.||.::.|.::.::..
  Fly   127 YHSVKTPVQTIVFSDLTVEGFKVASREKGLDWNHASLILQQLGKFHATSMVLAKKDPAIVKQYTR 191

  Fly   196 GIFNR--------HTQAFAPFFVNTVGVAADFARECPELGERYATKLKKLQERVMEYSTRVYDPQ 252
            |:.:.        ..|.|..|....:..:|.:|..     |:.:..|::|.:...........|:
  Fly   192 GMLSEDILMKSDTFEQMFGGFLKGLIKSSASWAGY-----EKISKHLQRLMDNFRNVCADAPRPR 251

  Fly   253 PGD-FNTLVHGDYWVNNVMLRYGENKEPLDMT---LIDFQFCSWSSPAVDLHYFFNTSVQVDIRY 313
            .|| :..|.|||.|.||.|..|....:|...|   .:|||...:.|||.||::|.|||:::.:..
  Fly   252 KGDRYVVLNHGDLWTNNFMYGYDNASQPDVPTRAIFVDFQLSFYGSPACDLNFFLNTSIKLQLLQ 316

  Fly   314 EQQDALFQYYHTVLVETLKDLNFGGYIPTLRQFVLQLERGR-------FFAVTVALVCQAILTND 371
            |:::.|.:.|:....:.|:...|.. ||:......:| |.|       .||....:.....|..|
  Fly   317 ERREELIKVYYASFKDALEYARFED-IPSYEDLQYEL-RSRETYGLFGMFAFLPMITMPKELAQD 379

  Fly   372 QNADADFNALMKDDERGRNFRKVLYTNKRLQDNLKRELPRFDRSGL 417
            .:.:.     |:|:...:.....:::.|.|.|:.|..|.|.|..|:
  Fly   380 NSIEN-----MQDEAFKQRKMDAIFSQKFLNDHQKWALKRADSLGV 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10513	NP_651370.2	EcKinase	50..336	CDD:281023	86/307 (28%)
CG9498	NP_609015.2	EcKinase	47..339	CDD:281023	86/307 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459181
Domainoid	1	1.000	62	1.000	Domainoid score	I6837
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	9	8.860