DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10513 and CG9497

DIOPT Version :9

Sequence 1:	NP_651370.2	Gene:	CG10513 / 43051	FlyBaseID:	FBgn0039311	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_001260130.1	Gene:	CG9497 / 33884	FlyBaseID:	FBgn0031800	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	432	Identity:	120/432 - (27%)
Similarity:	207/432 - (47%)	Gaps:	41/432 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DATEFHPAPEWLDETYLERLLRDLKNDPGLRITDLVIKPATAKGDNYASVMTRVRILFLKSGAKS 72
            ||....| |..||..:.|.:|........:::..:.|:..::.|:||.|.:.||::.|.:  ...
  Fly     7 DADVVAP-PSHLDVPFFEEVLETALRTARVQLLSIHIRMGSSTGENYCSQIYRVKVSFKR--PDH 68

  Fly    73 PETEY-YIVKTTYENDAFASGIFSQYQVSTTEMRMYEKILPQLSSLIEKTRQPEKVFAKTL--HV 134
            ||... :|||:....|:..  .....||...|...|.::||:|..|::..|:    |...|  ::
  Fly    69 PEQHMAFIVKSIPHLDSVE--FIDDLQVYLKEKITYYEVLPRLELLMQCNRR----FGPKLYHYL 127

  Fly   135 DYEHEAIIFEDLAVTKYVLADRLVGFDLEHTRLGLRKLAKMHAAAAVLNERQPGLLTKFDHGIFN 199
            .....:::|||||...:|:|.|.:|.:.||.:|.:.:||:.||.:..|....|.:...:..|:.:
  Fly   128 KQPENSLVFEDLAEKGFVMASRELGLNEEHCQLVMERLAEFHATSMALAVVDPHIFDAYGDGMLS 192

  Fly   200 RHTQAFAPFFVNTVGVAAD-------FARECPELGERYAT--KLKKLQERVMEYS-------TRV 248
            ..            |:|.|       |:....||....:|  ..:|:.|::.:|.       .|.
  Fly   193 PR------------GLAKDDGLLMQFFSGNGKELHHLVSTWPGFEKIAEKIGKYMQNQRANLERS 245

  Fly   249 YDPQPGDFNTLVHGDYWVNNVMLRYGENKEPLDMTLIDFQFCSWSSPAVDLHYFFNTSVQVDIRY 313
            ..||..:...|.|||.||||::.:|...:.|.|:.|||||...|.||.:||:|||.||:.:::..
  Fly   246 QAPQEKEVKVLNHGDLWVNNMLFKYDGAQRPQDLILIDFQLSVWGSPGIDLNYFFYTSLTLEVLR 310

  Fly   314 EQQDALFQYYHTVLVETLKDLNFGGYIPTLRQFVLQLERGRFFAVTVALVCQAILTNDQNADADF 378
            .::..|.:.||..|.:||.||:.|..:|:..|.:.::.|...:....:......::.|:...||.
  Fly   311 HRRTQLLRTYHARLAKTLLDLDMGIPVPSYEQILEEVHRRESYGFFASYGIFPTVSQDKAQTADN 375

  Fly   379 N-ALMKDDERGRNFRKVLYTNKRLQDNLKRELPRFDRSGLLD 419
            | ...||.:..:...:.::.::||.|.|:..||.|:|:|:||
  Fly   376 NLENFKDADFAKQKVRQMFQSRRLADTLRYTLPHFERAGVLD 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10513	NP_651370.2	EcKinase	50..336	CDD:281023	90/304 (30%)
CG9497	NP_001260130.1	EcKinase	49..331	CDD:281023	88/301 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459199
Domainoid	1	1.000	62	1.000	Domainoid score	I6837
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	9	8.860