DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10513 and CG7135

DIOPT Version :9

Sequence 1:	NP_651370.2	Gene:	CG10513 / 43051	FlyBaseID:	FBgn0039311	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_573269.1	Gene:	CG7135 / 32793	FlyBaseID:	FBgn0030895	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	434	Identity:	114/434 - (26%)
Similarity:	199/434 - (45%)	Gaps:	41/434 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DATEFHP---APEWLDETYLERLLRDLKNDP-GLRITDLVIKPATAKGDNYASVMTRVRILFLKS 68
            ||.|..|   .|::...| ||..|:.|.... |:::|:|     |..|:||.|.:.|.:|.:..:
  Fly     3 DALEEPPLYLTPQFFRRT-LEHGLQQLDLQVIGVQLTNL-----TRGGENYCSNIYRAQIKYRNA 61

  Fly    69 GAKSPETEYYIVKTTYENDAFASGIFSQYQVSTTEMRMYEKILPQLSSLIEK--------TRQPE 125
            .:.:.||...:.....|..|    |.::..:...|...|..|.|:|.:|:.:        |..|:
  Fly    62 ESCAMETSLIVKSMPDEKQA----ILARLHIYNKETLFYMHIKPKLEALMWRAVDSFSAWTLAPK 122

  Fly   126 KVFAKTLHVDYEHEAIIFEDLAVTKYVLADRLVGFDLEHTRLGLRKLAKMHAAAAVLNERQP-GL 189
            ..::.|    ...:.||.|||....|.|..|.:|.|.:|..|.:.|||:.||...|:.||:| .:
  Fly   123 HYYSTT----QPEQTIILEDLCAAGYQLKCRQLGLDFDHAALVMAKLAEYHALTMVMAEREPETI 183

  Fly   190 LTKFDHGIFNR---HTQAFAPFFVNTVGVAADFARECPELGERYATKLKKLQERVMEYSTRVYDP 251
            :.::..|:.:.   :::.|...|...:...|....:|...| ...|||.:..|...|...:...|
  Fly   184 VDRYPFGLLHMDAINSEPFKLLFGTQLLKLAALVGDCEGFG-GITTKLYRYHEHFTERVLKAVYP 247

  Fly   252 QPGDFNTLVHGDYWVNNVMLRYGENKEPLDMTLIDFQFCSWSSPAVDLHYFFNTSVQVDIRYEQQ 316
            ..|:.|.|.|||.||||:..:|........:.:||||.|.:.|...|::||.|||:::::..:::
  Fly   248 LRGNHNVLNHGDLWVNNIFFKYDAEYTVQQVKIIDFQLCFYGSLGFDINYFLNTSLELEVLRDRR 312

  Fly   317 DALFQYYHTVLVETLKDLNFGGYIPTLRQFVLQLERGRFFAVTVA-----LVCQAILTNDQNADA 376
            ..|...|:..||:.||.|.:...:|:....:.::.:...:...||     |:....:.::.|:..
  Fly   313 QELVDIYYRSLVDCLKHLPWSKELPSYEDIMDEIRKREAYGFFVAFGFFPLMSMIGVDSEDNSLK 377

  Fly   377 DFNALMKDDERGRNFRKVLYT-NKRLQDNLKRELPRFDRSGLLD 419
            :|:    |:...|...::::. |.|..::||..|.|.|...|.|
  Fly   378 NFH----DETFARQKVQLMFEGNTRTLESLKCTLKRLDELKLFD 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10513	NP_651370.2	EcKinase	50..336	CDD:281023	83/297 (28%)
CG7135	NP_573269.1	EcKinase	43..330	CDD:281023	82/295 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459190
Domainoid	1	1.000	62	1.000	Domainoid score	I6837
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	9	8.860