DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10513 and CG13360

DIOPT Version :9

Sequence 1:	NP_651370.2	Gene:	CG10513 / 43051	FlyBaseID:	FBgn0039311	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_569859.1	Gene:	CG13360 / 31025	FlyBaseID:	FBgn0025620	Length:	421	Species:	Drosophila melanogaster

Alignment Length:	418	Identity:	117/418 - (27%)
Similarity:	198/418 - (47%)	Gaps:	19/418 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 HPAPEWLDETYLERLLRDLKNDPGLRITDLVIKPAT-AKGDNYASVMTRVRILFLKSGAKSPETE 76
            |..|::|:|.:.:..|.|...|..:.|..::...:: ..|:||.|.:.|.:.|:..|..:..|..
  Fly    12 HEPPKYLNEDFFKAALEDGLRDMRVDIKKIIFSESSGGGGENYCSKIYRAKALYRSSKRQLDEEL 76

  Fly    77 YYIVKTTYENDAFASGIFSQYQVSTTEMRMYEKILPQLSSLIEKTRQPEKVFAKTLHVDYEH-EA 140
            ..|||:.....  |:....:..|...|...|..:|.:|..||   ....|..||.|:...|. :.
  Fly    77 ALIVKSIAITP--ATQFLEELAVYLREKIFYFDVLGKLEVLI---GDGSKFGAKCLYTTREPIQT 136

  Fly   141 IIFEDLAVTKYVLADRLVGFDLEHTRLGLRKLAKMHAAAAVLNERQPGLLTKFDHGIFN----RH 201
            |:|:||....|.||.|..|.:.||..:.|:||.|.||::.||.|::|.:...|..|:.:    |.
  Fly   137 IVFDDLTQYGYKLASRQSGLNEEHCVVILKKLGKFHASSMVLAEKEPSVREHFTTGMLDENYIRT 201

  Fly   202 TQAFAPFFVNTVGVAADFARECPELGERYATKLKKLQERVMEYSTRVYDPQPGDFNTLVHGDYWV 266
            .:.|..|........|:...:.|.. |..|.||.:..:.:.|.......|.||:...|.|||.||
  Fly   202 NERFINFMTLQCRTLANVVSKWPGY-ELLAEKLHRHCDNIKENLVTTGRPLPGEITVLNHGDLWV 265

  Fly   267 NNVMLRYGENK--EPLDMTLIDFQFCSWSSPAVDLHYFFNTSVQVDIRYEQQDALFQYYHTVLVE 329
            ||.|.:|.:.:  :|:|...:|||...:.||..|:::|.|:|||:|:...:::.|.|.|:..|.:
  Fly   266 NNFMYKYDDEQPTKPIDAIFVDFQNSFFGSPGCDINFFLNSSVQLDVLIHRREFLIQTYYASLRD 330

  Fly   330 TLKDLNFGGYIPT---LRQFVLQLERGRFFAVTVALVCQAILTNDQNADADFNALMKDDERGRNF 391
            :|:.:: ..::|:   ::|.:...|...||: :.|.:....:..:.:.|....||...|...:..
  Fly   331 SLERMH-SAFVPSYADIQQEIRARELYGFFS-SYAFLPMVTMKKEDSYDISIEALSDQDFAKKKV 393

  Fly   392 RKVLYTNKRLQDNLKRELPRFDRSGLLD 419
            :.:..:|.|..|.|:..|.|||..|:.|
  Fly   394 QLMFSSNPRTTDTLRYALRRFDDLGIFD 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10513	NP_651370.2	EcKinase	50..336	CDD:281023	89/292 (30%)
CG13360	NP_569859.1	EcKinase	50..335	CDD:281023	89/290 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459172
Domainoid	1	1.000	62	1.000	Domainoid score	I6837
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	9	8.860