DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11878 and CG14314

DIOPT Version :9

Sequence 1:	NP_651369.1	Gene:	CG11878 / 43050	FlyBaseID:	FBgn0039310	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_650690.1	Gene:	CG14314 / 42179	FlyBaseID:	FBgn0038581	Length:	438	Species:	Drosophila melanogaster

Alignment Length:	404	Identity:	91/404 - (22%)
Similarity:	161/404 - (39%)	Gaps:	56/404 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LTSEYVQDKLRTYFK--DSSLKLATLDTKPAVANGGNYGSVMTRINVEYTTKVSKGKQSTTFLV- 77
            |:.|..||    .||  :..:::...:.......|.||.:.:.||.:....:..|.:|:....|
  Fly    26 LSLEVFQD----IFKHVEPDVQIDAFELAQGSDRGDNYTAALYRIKLTGKRRSLKWEQNVICKVM 86

  Fly    78 -KTTFADRDPAGDVLIHYGVYTREMDIYEHILPQLADMVRKELKDSRKLFAATMNVDRER-DSII 140
             ::..|......|.|     :..|:..|..|:|:|......:......:|.|.......| |.:|
  Fly    87 PESVVAREAYKSDKL-----FRNEVQFYNTIMPELLKFQASKTNQDTPVFNAIPKCYSARHDLLI 146

  Fly   141 FEDMSLDHYKVACRRKKLDLEHTHLVLEKLALFHAASSVLAERQP------------GIF---DK 190
            .||:....::::.|.|.|.||.|..||.::|..|..|......:|            |||   :.
  Fly   147 MEDLRERGFQMSDRHKGLSLEETQSVLLQVAQLHGLSLAYKFEKPLEFSNLCSMISEGIFCTANT 211

  Fly   191 NYDRGFFNKHTRAYAPIMTNLLEALSRSLASDEELGQRYKAKIDRLVERLMDYG---ERSTTSSP 252
            ::.|.::.:.|:       |.::.:|..|..|    .:|...:::..|....:|   :.::|.||
  Fly   212 SWYRNYYERLTK-------NAIQMVSEVLPPD----SKYVLAMNKFAESSSFFGRMVKLASTESP 265

  Fly   253 GDFLTLAHGDLWTTNFMFQYDAKEHPTNAI---FIDFQFSVWNSPAIDLHYFFSTSLQDNLRLEH 314
              ...:.|||.|..||::.|| .|.|...:   .:|||...::|.|:|:...........:|...
  Fly   266 --LSAICHGDCWVNNFLYHYD-PEDPHRVLEVALLDFQLIRYSSIALDIANLLYCCTTKEMRDAQ 327

  Fly   315 QTELVQFYYYRLTEALRKL-----KYAGRIPSLFD-FQLQFRSRGFYAVFCSLIFEPVMQYEGKE 373
            ...|::.|...|...|:.|     .:...:..|.| |..:.::.|.:|:..:|...|:... ..|
  Fly   328 LQTLLKIYTEELFRWLQMLCTNLPDHCDTLQKLQDLFAEELKTYGRFALGLALDILPISTC-SSE 391

  Fly   374 DASIEQVLSSSESG 387
            ||....:..|.|.|
  Fly   392 DAPDMYLDRSDELG 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11878	NP_651369.1	EcKinase	47..335	CDD:281023	72/316 (23%)
CG14314	NP_650690.1	EcKinase	56..346	CDD:281023	71/308 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	3	3.010