DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11878 and CG6830

DIOPT Version :9

Sequence 1:	NP_651369.1	Gene:	CG11878 / 43050	FlyBaseID:	FBgn0039310	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster

Alignment Length:	418	Identity:	107/418 - (25%)
Similarity:	203/418 - (48%)	Gaps:	21/418 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PVWLTSEYVQDKLRTYFKDSSLKLATLDTKPAVANGGNYGSVMTR--INVEYTTKVSKGKQSTTF 75
            |.||.....::.|.... |...|:.....|||:|.|.||.::|.|  |:||.|.|.:|   ..:|
  Fly    47 PKWLNQTQFEELLAADV-DQFSKIVGFRVKPAMAPGENYATLMLRISIDVELTDKSTK---LVSF 107

  Fly    76 LVKTTFADRDPAGDVLIHYGVYTREMDIYEHILPQLADMVRK---ELKDSRKLFAATMNVDRE-- 135
            ::|... |......::.....:|.|...|..|||::.::.:.   ::|.:.:.|  .::..:|
  Fly   108 MMKVPH-DTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRAF--KLDATKEPK 169

  Fly   136 -RDSIIFEDMSLDHYKVACRRKKLDLEHTHLVLEKLALFHAASSVLAERQPGIFDKNYDRGFFNK 199
             .::::..|:..:.:|...|.:.|:||.|...|.:||.||||.:.:.:.. |.:...:..|....
  Fly   170 VANTVLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVH-GPYPDIFVNGVMGN 233

  Fly   200 HTRAYAPIMTNLLEALSRSLASDEEL---GQRYKAKIDRLVERL-MDYGERSTTSSPGDFLTLAH 260
            :..|....|..:|.:...|..::.:.   |:.|:.|:::.:..| |::.:.... .|.:|..|.|
  Fly   234 NKEAIIAFMEGMLASFRTSFMANLDKFKNGEEYREKLEKALAGLTMEFMKLGIV-DPNEFNALNH 297

  Fly   261 GDLWTTNFMFQYDAKEHPTNAIFIDFQFSVWNSPAIDLHYFFSTSLQDNLRLEHQTELVQFYYYR 325
            ||.|..|.:|:.::.....:.:|:|||...:.|||:||.||..:|:|.:.:|.|....::.|...
  Fly   298 GDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSVQIDYKLSHFDFFIRHYQEA 362

  Fly   326 LTEALRKLKYAGRIPSLFDFQLQFRSRGFYAVFCSLIFEPVMQYEGKEDASIEQVLSSSESGMRF 390
            |.:.|..|.:.||.|||.:........|.:.:|.::...|::..:..:.|:.:..:|.|..|:.|
  Fly   363 LVKHLGILGFTGRKPSLRELHRTLIKYGGWVLFPTISVLPLVLLDPTQSATFDNFMSDSADGVSF 427

  Fly   391 KNSVYESENIKKKLSVTLPFLDQFGLLD 418
            :.|:|.::..::.:...||:||..|.|:
  Fly   428 RGSLYANKRCQEYIERILPWLDNRGFLE 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11878	NP_651369.1	EcKinase	47..335	CDD:281023	76/299 (25%)
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	76/299 (25%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459356
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950