DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RIOK2 and AT3G51270

DIOPT Version :9

Sequence 1:	NP_651365.1	Gene:	RIOK2 / 43046	FlyBaseID:	FBgn0039306	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_001326514.1	Gene:	AT3G51270 / 824290	AraportID:	AT3G51270	Length:	461	Species:	Arabidopsis thaliana

Alignment Length:	499	Identity:	203/499 - (40%)
Similarity:	298/499 - (59%)	Gaps:	80/499 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KLNVTVLRYLTKEDFRVLTAIEMGMKNHELVPGPLAAAIANLKSGGVHKLLKELCKHKLLAYERG 67
            ||:|.|||||:|:|||||||:||||:|||:||..|...||.||.||.:|:||.|.|:|||.:: .
plant     2 KLDVNVLRYLSKDDFRVLTAVEMGMRNHEIVPSELVERIACLKHGGTYKVLKNLLKYKLLHHD-S 65

  Fly    68 KKYDGYRLTNTGYDYLALKSLTLRGSVSSFGNQIGIGKESNIYVVADEEGTPICLKLHRLGRTCF 132
            .||||:|||..|||:||:|:|..||..:..|.|||:||||:|:.||.|:||.:.:||||||||.|
plant    66 SKYDGFRLTYLGYDFLAIKTLVNRGIFTGVGRQIGVGKESDIFEVAQEDGTILAMKLHRLGRTSF 130

  Fly   133 RNVKAKRDYHGRRHKASWLYLSRISATREFAYMSALYDRGFPVPKPIDFNRHCVLMDLVKGWPMT 197
            |.||:||||...|...|||||||::|.:|||:|.||.:..|||||.||.|||||:|.||:|:||.
plant   131 RAVKSKRDYLRHRSSFSWLYLSRLAALKEFAFMKALEEHDFPVPKAIDCNRHCVIMSLVQGYPMV 195

  Fly   198 QVHELLDAPQVYDDLMNLIVRLGNSGVIHGDFNEFNLMVTDAGKPILIDFPQMMSTSHENAEFFF 262
            ||.:|.:...:::.::.::|||...|:||.||||||:|:.|..|..:||||||:|.||.||:.:|
plant   196 QVKQLQNPETIFEKIIGIVVRLAEHGLIHCDFNEFNIMIDDEEKITMIDFPQMVSVSHRNAQMYF 260

  Fly   263 ERDVNCVREMFRRKFGY-------ESED-------YPKFSDLVRE-DDLDAEVHCTGYGFTKEME 312
            :||:.|:.:.||::|..       |||:       .|.|.|:.:: :.||.::..:  |||:: |
plant   261 DRDIECIFKFFRKRFNMSFHEDKGESEETEVDENSRPSFFDITKDANALDKDLEAS--GFTRK-E 322

  Fly   313 QDLLEEY--GMVDQADEEDEGEDLEEEEEPPTLVTAASVE---IDECRR-QVENEVIYSEAKPTQ 371
            |..|:::  |.|:::::.||.|:.::||:     |..|.|   ::|.:. |::::        .|
plant   323 QTDLDKFIEGGVEKSEDSDEDEESDDEEQ-----TCESNEEGNLNEIKSLQLQDK--------EQ 374

  Fly   372 KSDDAVRRYIESCTQYLGNLSVGPEVPDQTMPKKLDISLPAETPDVIPFEAETSATNTVEEDVKS 436
            ||.|.|...:|                       ||             ..|...:|..|::|
plant   375 KSSDGVEAEVE-----------------------LD-------------NTENGESNGDEDEV-- 401

  Fly   437 ISSNDLDTDEVPELVGLDPNSRMYRLKMVEQMLNDARSQRSYST 480
             .||:.:.::..|   |:.|....|.:.:.......:||.|.:|
plant   402 -GSNEEEEEKEAE---LEKNLGKVRRRAMAAARGRRKSQSSRNT 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RIOK2	NP_651365.1	RIO2	3..282	CDD:223554	156/285 (55%)
		Rio2_N	9..91	CDD:286310	50/81 (62%)
		RIO2_C	94..276	CDD:270695	98/181 (54%)
AT3G51270	NP_001326514.1	RIO2	1..326	CDD:223554	168/327 (51%)
		Rio2_N	8..89	CDD:286310	50/81 (62%)
		RIO2_C	93..274	CDD:270695	98/180 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	203	1.000	Domainoid score	I856
eggNOG	1	0.900	-	-		E1_COG0478
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6760
Inparanoid	1	1.050	344	1.000	Inparanoid score	I633
OMA	1	1.010	-	-		QHG53873
OrthoDB	1	1.010	-	-		D1010730at2759
OrthoFinder	1	1.000	-	-		FOG0005212
OrthoInspector	1	1.000	-	-		oto4247
orthoMCL	1	0.900	-	-		OOG6_101547
Panther	1	1.100	-	-	LDO	PTHR45852
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3725
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840