DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10425 and kdsr

DIOPT Version :9

Sequence 1:	NP_651363.1	Gene:	CG10425 / 43043	FlyBaseID:	FBgn0039304	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001072722.1	Gene:	kdsr / 780179	XenbaseID:	XB-GENE-985089	Length:	332	Species:	Xenopus tropicalis

Alignment Length:	332	Identity:	129/332 - (38%)
Similarity:	198/332 - (59%)	Gaps:	5/332 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IVFCVGIAVLVHVLVYVF--VMAKKPRSIVGRHVVVTGGSKGIGLCLAVECAMKGANVTVIARDE 69
            ::......|...:|:|:.  :::.||..:.|.||||||||.|||.|:||||..:||.:|::||||
Frog     2 LLLAAAFLVAFVLLLYMVSPLISPKPLKLAGAHVVVTGGSSGIGKCVAVECFKQGAFITLVARDE 66

  Fly    70 KMLSGAVALMEVIRQRPDQKFQYRSLDISGDYDQVAKVLGEIEDSFGPIYTLINCAGMAICGVFE 134
            ..|..|...:|.......|.....|:|||.||.||..|:.:.::..||:..|:|||||||.|.||
Frog    67 GKLVQAKKEIEKYSINDKQVVLCISVDISKDYRQVENVIKQAQEKLGPVDMLVNCAGMAIAGNFE 131

  Fly   135 EVSVQDVHKLMNVNFFGTYNCTRYVLPKMKKAGDGIIVITASQAAMFGIYGYGPYSATKYALRAM 199
            |:.:....:||.:|:.|:...:|.|:..||:...|.||..:|||...|::||..||.||:|||.:
Frog   132 EIEIDKFARLMEINYLGSVYPSRAVISTMKERRMGRIVFVSSQAGQLGLFGYTAYSPTKFALRGL 196

  Fly   200 AETIAMESREHGVSVTLAMPCDTNTPGFEEEEKSKPRETKIISGGGGLIEPEVMAKAILKDALKG 264
            ||.:.||.:.:.:.||:|.|.||:||||.||.|:||.|||:||....|.:.:.:|:.|:|||::|
Frog   197 AEALQMEVKPYNIYVTVAYPPDTDTPGFAEENKTKPLETKLISESSSLCQADQVARVIVKDAIQG 261

  Fly   265 KFTSTVGAESWLITTLGGALLPWDGFFTNLLHAIVLGPLRIVSYALHKYFNSVIRKCAREDKAKA 329
            .|.|:||::.:::::|...:.|.......|...:.:|..||::......|:|::|:|..:   |.
Frog   262 NFNSSVGSDGYMLSSLTCGMSPVTTITEGLQQVVTMGLFRIIALFYLGSFDSIVRRCMIQ---KH 323

  Fly   330 TSQVESK 336
            .||...|
Frog   324 NSQKSCK 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10425	NP_651363.1	KDSR-like_SDR_c	35..271	CDD:187643	108/235 (46%)
CG10425	NP_651363.1	adh_short	36..229	CDD:278532	88/192 (46%)
kdsr	NP_001072722.1	KDSR-like_SDR_c	32..268	CDD:187643	108/235 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	176	1.000	Domainoid score	I3569
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H1539
Inparanoid	1	1.050	240	1.000	Inparanoid score	I3263
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1210617at2759
OrthoFinder	1	1.000	-	-		FOG0004308
OrthoInspector	1	1.000	-	-		oto104570
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1429
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060