DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10425 and SPCC1450.15

DIOPT Version :9

Sequence 1:	NP_651363.1	Gene:	CG10425 / 43043	FlyBaseID:	FBgn0039304	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_588314.2	Gene:	SPCC1450.15 / 2539289	PomBaseID:	SPCC1450.15	Length:	494	Species:	Schizosaccharomyces pombe

Alignment Length:	301	Identity:	79/301 - (26%)
Similarity:	137/301 - (45%)	Gaps:	39/301 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RHVVVTGGSKGIGLCLAVECAMKGANVTVIARDEKMLSGAVALMEVIRQRPDQKFQYRSLDISGD 100
            :|::|||||:|:|..:|.|..::|||||::||....|..|||.:...:...||:..:.|:|:: .
pombe    14 KHILVTGGSQGLGKAIAKELVLRGANVTIVARTVTKLQEAVAELSDSKIHEDQQVSFESVDLT-S 77

  Fly   101 YDQVAKVLGEIEDSFGPIYTLINCAGMAICGVFEEVSVQDVHKLMNVNFFGTYNCTRYVLPKMKK 165
            |:.|..::..:  .|.|.: :::|||..|.|.|.|:......|.|..|:..:.......:.:||:
pombe    78 YESVHSMIERL--PFCPDH-VVHCAGSCIPGFFTELDPSVFEKQMRQNYLASVYVCHAAIRRMKE 139

  Fly   166 AGDGI---IVITASQAAMFGIYGYGPYSATKYALRAMAETIAMESREHGVSVTLAMPCDTNTPGF 227
            .....   |::..|..:...|.||..||..|.|:|.:|:::..|...:.:.|::.:|....:||:
pombe   140 ISPSYSRRILLVGSLLSSLPIIGYSAYSPVKAAVRNLADSLRQECILYDIEVSVYLPSTILSPGY 204

  Fly   228 EEEEKSKPRETKIISGGGGLIEPEVMAKAILKDALKGKFTSTVGAES------------------ 274
            |:|...||.....:.|...:...|..|...:....:|.|  .:..||
pombe   205 EQENTLKPELVLQMEGMDSVQTCEEAASHCMTGLDRGDF--LIANESTGHLMKNHCRNSSPHDNP 267

  Fly   275 ---WLITTLGGALLPWDGFFTNLLHAIVLGPLRIVSYALHK 312
               :|...:  :||.|. |:...|.::|      ..|||.|
pombe   268 ILEYLFALV--SLLAWP-FYRRKLDSLV------YQYALEK 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10425	NP_651363.1	KDSR-like_SDR_c	35..271	CDD:187643	66/237 (28%)
CG10425	NP_651363.1	adh_short	36..229	CDD:278532	57/195 (29%)
SPCC1450.15	NP_588314.2	KDSR-like_SDR_c	13..251	CDD:187643	68/242 (28%)
		adh_short	14..202	CDD:278532	55/191 (29%)
		PIG-F	324..490	CDD:284183
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	93	1.000	Domainoid score	I2000
eggNOG	1	0.900	-	-		E1_KOG1210
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004308
OrthoInspector	1	1.000	-	-		oto101673
orthoMCL	1	0.900	-	-		OOG6_102003
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1750
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.700