DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nup358 and AT1G52380

DIOPT Version :9

Sequence 1:	NP_001247302.1	Gene:	Nup358 / 43041	FlyBaseID:	FBgn0039302	Length:	2718	Species:	Drosophila melanogaster
Sequence 2:	NP_001322286.1	Gene:	AT1G52380 / 841668	AraportID:	AT1G52380	Length:	440	Species:	Arabidopsis thaliana

Alignment Length:	392	Identity:	91/392 - (23%)
Similarity:	146/392 - (37%)	Gaps:	95/392 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly  1152 PQVAPSVPAQP-------PAPAPVSVPSMFNRALNNQPVEKEPPANVVITSSDPLPKPTTASVQP 1209
            |..||...:.|       |..||.|.|...|..|..   .|..||..|:..:.     ..:.::.
plant    62 PSAAPVAASNPFAGIQLVPTTAPASTPVGTNAPLAE---SKLAPAEAVVEDNQ-----KASDIEE 118

  Fly  1210 TLSVTIPAQHIKPSLVQAPEQ----------PAQSAQPAQPSVSGVGSLSFNF------GSKSSE 1258
            ...|......:|.::.:..|:          .:...|.|...|:.:.|...|.      |:..::
plant   119 GDEVDSKKVDVKDAVGEETEKTKDKDDNHCGKSADVQVAATEVAQMVSCDTNVCNNAVEGTDQTD 183

  Fly  1259 SPFSFKTQVAKAAAEKQKEQ---EEAEQN------------------------------------ 1284
            .|.. |......|.:|:||.   |||::|
plant   184 FPLE-KDSGGDQAEKKEKEGNGIEEADKNGDNGAFSSFQQHSSNKNAFTGLASTEASGSSFSFGL 247

  Fly  1285 --QSGATDPNKT----LPQDTSADDYDPRPDFKPII--------PLPDEVEVRTGEEGEDIKFTS 1335
              |.|:|.....    ||...|:..:....  ..||        |...||...||||.|.:.|::
plant   248 VSQDGSTGTGSLFGFGLPSSNSSSIFGATG--SSIIKKSEGSGFPPKQEVSTETGEENEKVAFSA 310

  Fly  1336 RAKLFRYVDKEWKERGTGVIKILCDKATGVSRVLMRRDQTHKVCANHTITADITINVANQDKDKK 1400
            .:.:|.|:|..|||||.|.:|:......|.:|::||....:::..|.::..:  :.:||.  |||
plant   311 DSIMFEYLDGGWKERGKGELKVNVSSNDGKARLVMRAKGNYRLILNASLYPE--MKLANM--DKK 371

  Fly  1401 SLLWA-ANDFADEQVTLERFLVRFKTGELAEEFRVAFTKASEA---AKSKETVKPTVNTAEKGST 1461
            .:.:| .|..::.:..|..|.::||...:.||||||..|..::   .|:.|.....:.|.|...|
plant   372 GITFACVNSVSEGKEGLSTFALKFKDPTIVEEFRVAIDKHKDSKPMEKAAEKSALPLKTPENSPT 436

  Fly  1462 AT 1463
            ||
plant   437 AT 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nup358	NP_001247302.1	TPR	<14..128	CDD:223533
		TPR repeat	58..90	CDD:276809
		Atrophin-1	<1030..1308	CDD:331285	40/223 (18%)
		RanBD1_RanBP2_insect-like	1324..1442	CDD:269992	39/118 (33%)
		RanBD2_RanBP2_insect-like	1620..1737	CDD:269993
		RanBP2-type Zn finger	1774..1793	CDD:275376
		Nucleoporin_FG2	1806..>1986	CDD:330420
		RanBP2-type Zn finger	1833..1861	CDD:275375
		zf-RanBP	1891..1917	CDD:279035
		RanBP2-type Zn finger	1894..1913	CDD:275376
		RanBD3_RanBP2_insect-like	2034..2148	CDD:269994
		RanBD4_RanBP2_insect-like	2571..2694	CDD:269995
AT1G52380	NP_001322286.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5171
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23138
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910