DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sil1 and sil1

DIOPT Version :9

Sequence 1:	NP_651356.1	Gene:	Sil1 / 43034	FlyBaseID:	FBgn0039296	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001096338.1	Gene:	sil1 / 100124924	XenbaseID:	XB-GENE-5898521	Length:	453	Species:	Xenopus tropicalis

Alignment Length:	428	Identity:	121/428 - (28%)
Similarity:	194/428 - (45%)	Gaps:	52/428 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 VAAATETDNKTND---FVATDEWQTIAEGQAIPRGLHVRINLQTGLKEAKLLD------------ 70
            |.|..|.:....|   |..|.|||.:..|||:|.|||:|:|||||..||||.|
Frog    49 VEAFVENEQDPEDLEIFYPTQEWQVVKPGQAVPAGLHMRLNLQTGKNEAKLPDGQDGKDRPKQTH 113

  Fly    71 ESERGTSLQSQPDDQNARESHDDNEPLA----LDYKPDIIEESIRRVKEQKKSYAELRKAYKEFQ 131
            :|...:.:.|..:.:.|......:|.|:    .||:.||        |::.:...:|:||:.:..
Frog   114 KSSTISDVYSTKELKEALAKFKGDEKLSPAEGKDYQQDI--------KQRFRPIEDLKKAFDDLN 170

  Fly   132 KNFRTDGELIVQLIDQFRNFSRTPLESEMRSKLDCLENLEYLLHQIDNALMFIDNGGLDDVLLPI 196
            .|..||.|::.::|::|.:.|.|.      .|:..|.:|||.:||:|||...:..|||.  ||..
Frog   171 INVETDIEIMTKIINKFNSSSSTV------EKVSALYDLEYYVHQVDNAQNLLKLGGLQ--LLIN 227

  Fly   197 VVNDTSTSLRVSAMRVLGSLASNNPKAQIKVFEKNFGSHLAQILTSSGNVGEISAALHAFGALLR 261
            .:|.|...|...:..|:||..|:|||.||:.||......|..||.:...|......|:|..::||
Frog   228 SLNSTDPLLIEHSAFVIGSALSSNPKVQIEAFEAGALQKLLVILAADQEVSVKKKTLYALSSMLR 292

  Fly   262 KFPLAQQRVLSTSGTQALIKVLQSPDVELRSKAKVVTLISDLVLEKRSVLDVSKDDPEASSTMAQ 326
            :||.||||.:...|.|.|....:..:|| ....:|:||:.|:::|| .:|....:..:......|
Frog   293 QFPYAQQRFMKLGGLQILKNFFKEKNVE-PLYIRVITLLYDMIMEK-MLLHKENNTGQYEQKYQQ 355

  Fly   327 YVLLDFESWLKTPGYCAAVDTVLTKEFLLLLEQPEVVEQFATALETTEDMCTSTWSQSSGLRHAL 391
            |..::....:...|:|..:..      ||.|.:.:..|:....:......|.:.:.....||..|
Frog   356 YNQINLLESIIEQGWCPIISD------LLKLPENDAREKVLKTVMILIPHCRAEFLNDENLRTIL 414

  Fly   392 LTVRNRY---------ANSTDEYRLEVSQILAKLCERL 420
            .::|..|         :...|.|..|:..:...:.::|
Frog   415 NSLRKEYEGLAADELNSGEQDGYFSELLSLTISINDKL 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sil1	NP_651356.1	SIL1	167..>326	CDD:374797	54/158 (34%)
sil1	NP_001096338.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	148	1.000	Domainoid score	I4416
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H32544
Inparanoid	1	1.050	149	1.000	Inparanoid score	I4284
OMA	1	1.010	-	-		QHG48752
OrthoDB	1	1.010	-	-		D1501690at2759
OrthoFinder	1	1.000	-	-		FOG0005609
OrthoInspector	1	1.000	-	-		oto104162
Panther	1	1.100	-	-	LDO	PTHR19316
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5248
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080