Protein Alignment Cad96Cb and Pcdhb3

DIOPT Version :9

• Sequence 1: NP_001287524.1
• Gene: Cad96Cb / 43033
• FlyBaseID: FBgn0039294
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_444358.2
• Gene: Pcdhb3 / 93874
• MGIID: 2136737
• Length: 784
• Species: Mus musculus
• Alignment Length: 730
• Identity: 176/730 - (24%)
• Similarity: 272/730 - (37%)
• Gaps: 191/730 - (26%)

  Fly    36 GGSAESFLATEDLAVGSIIGKLRINGDANAETGDINLS---LREKNAPV---------EIHPGTK 88
            |..:..:...|:...|.:|        ||..| |:.||   |.|:.|..         ::...|.
Mouse    27 GSMSRRYSVAEEKEKGFVI--------ANLAT-DLGLSIEELAERRAQAISKGNIQYFQLSHQTG 82

  Fly    89 ELALSVELDKEGVRGPSSIYVNVICIRRHSTDPSFVIPVNVRVTDVNDNAPQWIGTPYTLTLSEV 153
            :|.|..:||:|.:.|.:...|....|..|  ||...|...:.|.||||:||::......|.:.|.
Mouse    83 DLLLVEKLDREDLCGSTEPCVLHFQILLH--DPLQFITNELEVIDVNDHAPEFFENAMQLKVLEN 145

  Fly   154 TVPGTRILQGARAEDADQPGPFSTVEYQVLPGPYSEYVQFLNPLEG----TLVLKKALDYEQLQN 214
            :||||.|..| .|.|.| .|......|.|.|..:. :|......:|    .|||.:|||.|:...
Mouse   146 SVPGTVIPLG-NAVDLD-VGRNGLQNYTVSPTSHF-HVHTRRRRDGRKYPELVLDRALDREEQSE 207

  Fly   215 FTVKLRAQDQGTPPRHSDTLLRVVITDADDQNPKFQRESYSAEIPADGRPGELRMRPEPLKAV-- 277
            .::.|.|.|.|:|||...|.:.:::.|.:|..|:|.:..|..:|          :...|:.:|
Mouse   208 ISLTLTALDGGSPPRSGTTQVHILVLDTNDNAPEFTQSLYEVQI----------LEKSPIGSVIT 262

  Fly   278 -----DQDEGICAPIQYTIVQSQD--AKYFRIHPHNGAISLLTPIGY---------ADVANGATL 326
                 |.|.|....|.|....:.:  .:.||::...|.|.||..:.|         .:..:|..|
Mouse   263 TVSASDLDTGNFGAISYVFFHASEEILETFRLNSSTGNIQLLKGLDYEAINTYEVDIEAKDGGGL 327

  Fly   327 VVKATQI-------DNPDRYALTTVQLTRPGSH-------------------------------- 352
            ..|.|.|       |||....|::|....|.:.
Mouse   328 SGKCTVIVQILDVNDNPPELTLSSVNSLIPENSAETVVAVFSVSDLDSGDNGRVTCSIQNDLPFI 392

  Fly   353 -------------------------------SDLST--------------------LAFVQKRFV 366
                                           |||.|                    .||.|..:.
Mouse   393 LKPSVENFYTIASEWALDREIRAEYNITITVSDLGTPRLTTQHTITVQVSDLNDNAPAFTQTSYT 457

  Fly   367 MRIREDTAVGNRI--LALPTNKPGK--HLKYVIPDPVNSQFFSVGSL-------GELVLAKPLDY 420
            |.:||:.:....|  ::...:..|.  |:.|.:..|.:.| .::.||       |:|...:.|||
Mouse   458 MSVRENNSPALHIGTISATDSDSGSNAHITYSLLPPHDPQ-LALDSLISINADNGQLFALRALDY 521

  Fly   421 EKMTKHEFQVLATDG---MTNSTAELTLEVIDVNDWEPRFRETHYEFMVPKSSLQSRADSFEGVL 482
            |.:...||.|.||||   ..:|.|.:.:.|:|.||..|...........|.:.|..|| :..|.|
Mouse   522 EALQAFEFHVGATDGGSPALSSQALVRVVVLDDNDNAPFVLYPLQNASAPCTELLPRA-AETGYL 585

  Fly   483 IGKVEAADGDRNDKLELS---LRGQHAGLFEIDSTGNIYMRPEQLQSLNESTVHLIAIATDTGVP 544
            :.||.|.|.|......||   |:....|||.:.:..........|...:.....|:.:..|.|.|
Mouse   586 VTKVVAVDRDSGQNAWLSFQLLKSTEPGLFSVWAHNGEVRTARLLSERDMLKQKLLLLVKDNGDP 650

  Fly   545 PRSTSVPVSVTM-EGLT--------LARSGWNSNMLGMFGMIMGLFLMIIVA-------LSCYI- 592
            |||.||.::|.: :|.:        :||....:::     .::.|:|:|.:|       ||..:
Mouse   651 PRSASVTLNVLLVDGFSQPYLPLPEVARDSVQNDV-----DLLTLYLVIALASVSSLFLLSVLLF 710

  Fly   593 --VRSKKQGKSASSG 605
              ||..::.::||.|
Mouse   711 VGVRLCRRARAASMG 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Cb	NP_001287524.1	Cadherin_repeat	46..137	CDD:206637	29/102 (28%)
		Cadherin_repeat	145..244	CDD:206637	33/102 (32%)
		Cadherin_repeat	253..347	CDD:206637	26/118 (22%)
		Cadherin_repeat	365..452	CDD:206637	28/100 (28%)
		Cadherin_repeat	461..555	CDD:206637	27/96 (28%)
Pcdhb3	NP_444358.2	Cadherin_2	31..112	CDD:285466	22/91 (24%)
		Cadherin_repeat	139..238	CDD:206637	33/101 (33%)
		Cadherin_repeat	247..343	CDD:206637	21/105 (20%)
		Cadherin_repeat	356..447	CDD:206637	5/90 (6%)
		Cadherin_repeat	455..557	CDD:206637	29/102 (28%)
		Cadherin_repeat	576..664	CDD:206637	26/88 (30%)
		Cadherin_C_2	688..769	CDD:293101	11/38 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I4532
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050