Protein Alignment Cad96Cb and pcdh19

DIOPT Version :9

• Sequence 1: NP_001287524.1
• Gene: Cad96Cb / 43033
• FlyBaseID: FBgn0039294
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: XP_009289395.1
• Gene: pcdh19 / 555688
• ZFINID: ZDB-GENE-030131-4218
• Length: 1094
• Species: Danio rerio
• Alignment Length: 980
• Identity: 200/980 - (20%)
• Similarity: 335/980 - (34%)
• Gaps: 330/980 - (33%)

  Fly    15 LCWFNKATLGAILDSRCYLEGGGSAESFLATEDLAVGSIIGKLRINGDANAETGDINLSLRE--- 76
            |||   ..:.|:.:.:..:|           |:|..|:.|.    |..|:|:.....|..|:
Zfish    17 LCW---TGVDAVFNLKYTVE-----------EELRAGTKIA----NVTADAKVAGFALGNRQPYL 63

  Fly    77 ----KNAP--VEIHPG----TKELALSVELDKEGV-RGPSSIYVNV--------ICIRRHSTDPS 122
                .:.|  |.:.|.    ||:     ::|::.| |.....::::        ||:
Zfish    64 RVISNSEPRWVNLSPAGLLITKQ-----KIDRDAVCRQTPKCFISLEVMSNSMEICV-------- 115

  Fly   123 FVIPVNVRVTDVNDNAPQWIGTPYTLTLSEVTVPGTRI-LQGARAEDADQPGPFSTVEYQVLP-- 184
                :.:.:.|||||||::......:.:||...||||. |:||...|:...|   ...|.:.|
Zfish   116 ----IKIEIIDVNDNAPRFPTNHIDIEISENAAPGTRFPLEGASDPDSGSNG---IQTYTITPND 173

  Fly   185 ---------GPYSEYVQFLNPLEGTLVLKKALDYEQLQNFTVKLRAQDQGTPPRHSDTLLRVVIT 240
                     |..|:..:        ||::|.||.|....:|.:|.|:|.|.||:.....|.:.:.
Zfish   174 IFGLEIKTRGDGSKIAE--------LVVEKTLDRETQSRYTFELTAEDGGDPPKSGTVQLNIKVI 230

  Fly   241 DADDQNPKFQRESYSAEIPADGRPGELRMRPEPLKAVDQDEGICAPIQYT---IVQSQDAKYFRI 302
            |::|.||.|....|:..:..:.....|.:   .|.|.|.|||....:.|:   .|.:...:.|:|
Zfish   231 DSNDNNPVFDEPVYTVNVLENSPINTLVI---DLNATDPDEGTNGEVVYSFINFVSNLTKQMFKI 292

  Fly   303 HPHNGAIS------------------------------------------------LLT------ 313
            .|..|.|:                                                ||:
Zfish   293 DPKTGVITVNGVLDHEELHIHEIDVQAKDLGPNSIPAHCKVIVNVIDINDNAPEIKLLSENSEMV 357

  Fly   314 ------PIGYA----------DVANG--------------------ATLVVKATQIDNP--DRYA 340
                  |:||.          ..|||                    :||:|.. ::|..  |.|.
Zfish   358 EVSENAPLGYVIALVRVSDNDSGANGKVQCRLQGNVPFRLNEFESFSTLLVDG-RLDREQRDMYN 421

  Fly   341 LTTVQLTRPGSHSDLSTLAFVQKRFVMRIRED-------TAVGNRILALPTNKPGKHLKYV-IPD 397
            ||.  |.....:..|.:    .|.|.:::.::       |....:.:.|..|.||..|..| ..|
Zfish   422 LTI--LAEDSGYPPLRS----SKSFAVKVTDENDNPPYFTKPHYQAMVLENNVPGAFLLAVSARD 480

  Fly   398 P------------VNSQ--------FFSVGSLGELVLAKPLDYEKMTKHEFQVLATDG---MTNS 439
            |            :.|:        :.:|.|.||:...:..::|.....||:|.|.||   ...|
Zfish   481 PDLGMNGTVSYEIIKSEVRGMSVESYVTVNSNGEIYGVRAFNHEDTRTFEFKVSAKDGGDPPLTS 545

  Fly   440 TAELTLEVIDVND-----WEPRFRETHYEFMVPKSSLQSRADSFEGVLIGKVEAADGD--RNDKL 497
            .|.:.:.|:||||     ..|.......|..:||       ::..|.|:.:::|.|.|  .|.:|
Zfish   546 NATVRIVVLDVNDNTPVMTTPPLVNGTAEVSIPK-------NAGVGYLVTQIKADDYDEGENGRL 603

  Fly   498 ELSLRGQHAGLFEIDSTGNIYMRPEQLQSLNESTVHLIAIATDTGVPPRSTSVPVSVTME-GLTL 561
            ..|:.......||||.........:......:.:..:..:|.|.|....|.|..:.:.:. .|..
Zfish   604 TYSISEGDMAYFEIDQINGEVRTTKTFGENAKPSYQITVVAHDHGQTSLSASAYIVIYLSPDLNA 668

  Fly   562 ARSGWNSNMLGMFGMIMG-----LFL-MIIVALSC---------------YIVR----------- 594
            .......|:..:|.:.:|     ||: ||.||:.|               |:.|
Zfish   669 QEQIGPVNLSLIFIIALGSIAVILFVTMIFVAVKCKRDNKEIRTYNCSFLYLRRVAEYSYGNQKK 733

  Fly   595 SKKQGKSASSGLGLGRNRVHSQAHSSVSSANLVT--------HEKLAGNGNGNGASVTSGGVSVL 651
            |.|:.|.:.:.:.|....|......:|.|.:.:|        |::....|.....|      :.|
Zfish   734 SSKKKKLSKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRSES------TFL 792

  Fly   652 HMKHGGNITMANPMNNGLHHVASG---------------------ASSSMALGSSAALL------ 689
            :::: .|...|.| |:|.||..:|                     :..|..:.|.|.|:
Zfish   793 NVEN-QNSRNAAP-NHGYHHTFTGQGPQQPDLIINGMPLPETENYSIDSSYVNSRAHLIKSTSTF 855

  Fly   690 -------------ERERERERDRERQRESYAAT-----VRIFLPGIVSRASANGQLFEEDEIEHD 736
                         |...:.:.:.:.||..||.|     :.:.:|      |.|.|:.::|:.|..
Zfish   856 KDMEGNSLKDSGHEESDQTDSEHDVQRGHYADTAVNDVLNMTVP------SNNSQIPDQDQSEGF 914

  Fly   737 SLQTE 741
            ..|.|
Zfish   915 HCQDE 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Cb	NP_001287524.1	Cadherin_repeat	46..137	CDD:206637	22/112 (20%)
		Cadherin_repeat	145..244	CDD:206637	30/110 (27%)
		Cadherin_repeat	253..347	CDD:206637	31/188 (16%)
		Cadherin_repeat	365..452	CDD:206637	27/117 (23%)
		Cadherin_repeat	461..555	CDD:206637	20/95 (21%)
pcdh19	XP_009289395.1	E_set	28..107	CDD:298831	18/98 (18%)
		Cadherin_repeat	137..235	CDD:206637	30/108 (28%)
		Cadherin_repeat	243..343	CDD:206637	15/102 (15%)
		Cadherin_repeat	357..450	CDD:206637	18/99 (18%)
		Cadherin_repeat	458..559	CDD:206637	26/100 (26%)
		Cadherin_repeat	574..667	CDD:206637	20/99 (20%)
		Cadherin_C_2	676..>731	CDD:293101	12/54 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	130	1.000	Inparanoid score	I4620
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.050